Rabbit Anti-UGT2B4 Polyclonal Antibody – Cat# MBS646272

UGT2B4 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the UGT2B4 antibody detected the UGT2B4 protein (arrow).

UGT2B4 Antibody – Rabbit Polyclonal

Name: UGT2B4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS646272
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646272

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

UGT2B4, Polyclonal Antibody

Full Product Name

UGT2B4, NT (UGT2B4, UGT2B11, UDP-glucuronosyltransferase 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1)

Product Gene Name

anti-UGT2B4 antibody

Product Synonym Names

Anti -UGT2B4, NT (UGT2B4, UGT2B11, UDP-glucuronosyltransferase 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

60,513 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (70345883..70391732, complement). Location: 4q13

OMIM

600067

3D Structure

ModBase 3D Structure for P06133

Immunogen

UGT2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human UGT2B4.

Product Categories/Family for anti-UGT2B4 antibody

Antibodies; Abs to Enzymes; Glucuronosyltransferase

Applications Tested/Suitable for anti-UGT2B4 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-UGT2B4 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-UGT2B4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UGT2B4 purchase

MBS646272 is an antibody targeting UGT2B4. Also known as UGT2B4, NT (UGT2B4, UGT2B11, UDP-glucuronosyltransferase 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for UGT2B4. It may not necessarily be applicable to this product.

NCBI GI #

149944509

NCBI GeneID

7363

NCBI Accession #

NP_066962.2

UniProt Primary Accession #

P06133

UniProt Secondary Accession #

O60731; O60867; O75614; P36538; Q1HBF9

UniProt Related Accession #

P06133

GenBank Nucleotide #

NM_021139.2

NCBI Official Full Name

UDP-glucuronosyltransferase 2B4

NCBI Official Synonym Full Names

UDP glucuronosyltransferase 2 family, polypeptide B4

NCBI Official Symbol

UGT2B4

NCBI Official Synonym Symbols

HLUG25; UDPGTH1; UGT2B11; UDPGT2B4

UniProt Protein Name

UDP-glucuronosyltransferase 2B4

UniProt Synonym Protein Names

HLUG25; Hyodeoxycholic acid-specific UDPGT; UDPGTh-1

Protein Family

UDP-glucuronosyltransferase

UniProt Gene Name

UGT2B4

UniProt Synonym Gene Names

UGT2B11; UDPGT 2B4

UniProt Entry Name

UD2B4_HUMAN

NCBI Protein Information

UDP-glucuronosyltransferase 2B4; UDPGTh-1; UDPGT 2B4; hyodeoxycholic acid; UDP glucuronosyltransferase 2B4; hyodeoxycholic acid-specific UDPGT; UDP-glucuronyltransferase, family 2, beta-4

UniProt Comments for UGT2B4

Function: UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.

Catalytic activity: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

Subcellular location: Microsome membrane; Single-pass membrane protein

Potential. Endoplasmic reticulum membrane; Single-pass membrane protein

Potential.

Sequence similarities: Belongs to the UDP-glycosyltransferase family.

Caution: Ref.2 thought that this was a new form (UGT2B11). The name UGT2B11 has now been reused for another human enzyme.

Research Articles on UGT2B4

1. Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UGT2B4 antibody

Reference Product	PubMed Publications
CYP1A2 antibody	>6 publications with UGT2B4 and CYP1A2
CYP2D6 antibody	>6 publications with UGT2B4 and CYP2D6
CYP3A4 antibody	>6 publications with UGT2B4 and CYP3A4
CYP2C9 antibody	>3 publications with UGT2B4 and CYP2C9
CYP2B6 antibody	>2 publications with UGT2B4 and CYP2B6
CYP2C19 antibody	>1 publications with UGT2B4 and CYP2C19

Pathways associated with anti-UGT2B4 antibody

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Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
Chemical Carcinogenesis Pathway antibodies	Chemical Carcinogenesis Pathway Diagram
Chemical Carcinogenesis Pathway antibodies	Chemical Carcinogenesis Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Drug Metabolism - Other Enzymes Pathway antibodies	Drug Metabolism - Other Enzymes Pathway Diagram

Diseases associated with anti-UGT2B4 antibody

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>7 publications with UGT2B4 and Liver Diseases
Cholestasis Antibodies	>4 publications with UGT2B4 and Cholestasis
Carcinoma Antibodies	>4 publications with UGT2B4 and Carcinoma
Gastrointestinal Diseases Antibodies	>3 publications with UGT2B4 and Gastrointestinal Diseases
Hypertension Antibodies	>2 publications with UGT2B4 and Hypertension
Fatty Liver Antibodies	>2 publications with UGT2B4 and Fatty Liver
Liver Neoplasms Antibodies	>2 publications with UGT2B4 and Liver Neoplasms
Inflammation Antibodies	>2 publications with UGT2B4 and Inflammation
Carcinoma, Hepatocellular Antibodies	>2 publications with UGT2B4 and Carcinoma, Hepatocellular
Liver Cirrhosis, Experimental Antibodies	>1 publications with UGT2B4 and Liver Cirrhosis, Experimental

Organs/Tissues associated with anti-UGT2B4 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>66 publications with UGT2B4 and Liver
Kidney Antibodies	>6 publications with UGT2B4 and Kidney
Lung Antibodies	>5 publications with UGT2B4 and Lung
Heart Antibodies	>3 publications with UGT2B4 and Heart