• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PANX2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646294

Pannexin 2 (PANX2) is a~60kD, 677aa protein of the pannexin family of four-transmembrane channel proteins with a conserved pattern of cysteines. PANX2 can interact with PANX1. It is mainly expressed on postnatal neural progenitors and is thought to inhibit… More details

$955 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PANX2, Monoclonal Antibody
Full Product Name
PANX2 (Pannexin2)
Product Gene Name
Product Synonym Names
Anti -PANX2 (Pannexin2)
Clonality
Monoclonal
Isotype
IgG2B
Clone Number
12K156
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.5mg/ml.
Purity/Purification
Affinity Purified
Purified by Protein A/G affinity chromatography.
Specificity
Recognizes human Pannexin-2.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
74,447 Da
Chromosome Location
Chromosome: 22; NC_000022.10 (50609160..50618724). Location: 22q13.33
OMIM
608421
3D Structure
ModBase 3D Structure for Q96RD6
Immunogen
Recombinant corresponding to aa316-456 from human Pannexin-2 expressed in E.coli.

Product Categories/Family for anti-PANX2 antibody

Applications Tested/Suitable for anti-PANX2 antibody
Western Blot (WB)
Application Notes for anti-PANX2 antibody
Suitable for use in Western Blot.
Dilution: Western Blot: 0.5ug/ml

Western Blot (WB) of anti-PANX2 antibody

Detection of Human Pannexin-2 by Western Blot. Western blot shows lysates of human brain (cortex) tissue and human brain (hippocampus) tissue. PVDF membrane was probed with 0.5ug/ml of Mouse Human Pannexin-2 Monoclonal Antibody followed by HRP-conjugated Mouse IgG Secondary Antibody. A specific band was detected for Pannexin-2 at approximately 65kD. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
Mouse Anti-PANX2 Monoclonal Antibody – Cat# MBS646294

Other Notes

Small volumes of anti-PANX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PANX2 purchase

MBS646294 is an antibody targeting PANX2. Also known as PANX2 (Pannexin2). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PANX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pannexin-2 isoform 2
NCBI Official Synonym Full Names
pannexin 2
NCBI Official Symbol
PANX2
NCBI Official Synonym Symbols
PX2; hPANX2
UniProt Protein Name
Pannexin-2
Protein Family
UniProt Gene Name
PANX2
UniProt Entry Name
PANX2_HUMAN
NCBI Protein Information
pannexin-2

NCBI Summary for PANX2

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Show more

UniProt Comments for PANX2

Function: Structural component of the gap junctions and the hemichannels

By similarity.

Subunit structure: Forms PANX1/PANX2-heteromeric intercellular channels on coexpression in paired Xenopus oocytes. Does not form homomeric channels

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein

Potential. Cell junction › gap junction.

Sequence similarities: Belongs to the pannexin family.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PANX2 antibody

 Reference Product  PubMed Publications
 PANX1 antibody  >26 publications with PANX2 and PANX1
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000