Rabbit Anti-CHORDC1 Polyclonal Antibody – Cat# MBS646303

CHORDC1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CHORDC1 antibody detected the CHORDC1 protein (arrow).

CHORDC1 Antibody – Rabbit Polyclonal

Name: CHORDC1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS646303
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646303

CHORDC1 may be play a role in the regulation of NOD1 via its interaction with HSP90AA1 (By similarity). More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CHORDC1, Polyclonal Antibody

Full Product Name

CHORDC1, ID (CHORDC1, CHP1, Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, Protein morgana)

Product Gene Name

anti-CHORDC1 antibody

Product Synonym Names

Anti -CHORDC1, ID (CHORDC1, CHP1, Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, Protein morgana)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

37,490 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (89933597..89956532, complement). Location: 11q14.3

OMIM

604353

3D Structure

ModBase 3D Structure for Q9UHD1

Immunogen

CHORDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the Central region of human CHORDC1.

Product Categories/Family for anti-CHORDC1 antibody

Antibodies; Abs to Amino Acids

Applications Tested/Suitable for anti-CHORDC1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-CHORDC1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-CHORDC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHORDC1 purchase

MBS646303 is an antibody targeting CHORDC1. Also known as CHORDC1, ID (CHORDC1, CHP1, Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, Protein morgana). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CHORDC1. It may not necessarily be applicable to this product.

NCBI GI #

221316570

NCBI GeneID

26973

NCBI Accession #

NP_001137545.1

UniProt Primary Accession #

Q9UHD1

UniProt Secondary Accession #

Q6IN49; Q8WVL9; Q9H3D6; B2R6P8

UniProt Related Accession #

Q9UHD1

GenBank Nucleotide #

NM_001144073.1

NCBI Official Full Name

cysteine and histidine-rich domain-containing protein 1 isoform b

NCBI Official Synonym Full Names

cysteine and histidine-rich domain (CHORD) containing 1

NCBI Official Symbol

CHORDC1

NCBI Official Synonym Symbols

CHP1

UniProt Protein Name

Cysteine and histidine-rich domain-containing protein 1

UniProt Synonym Protein Names

CHORD domain-containing protein 1; CHORD-containing protein 1; CHP-1; Protein morgana

Protein Family

Cysteine and histidine-rich domain-containing protein

UniProt Gene Name

CHORDC1

UniProt Synonym Gene Names

CHP1; CHORD-containing protein 1; CHP-1

UniProt Entry Name

CHRD1_HUMAN

NCBI Protein Information

cysteine and histidine-rich domain-containing protein 1; CHP-1; protein morgana; CHORD-containing protein 1; chord domain-containing protein 1; cysteine and histidine-rich domain (CHORD)-containing 1; cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1

UniProt Comments for CHORDC1

Function: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis. Ref.10

Subunit structure: Interacts with HSP90AA1, ROCK1 and ROCK2. Interacts with HSP90AB1 and PPP5C

By similarity. Ref.10 Ref.11

Tissue specificity: Underexpressed in many breast and lung cancers. Ref.10

Sequence similarities: Contains 2 CHORD domains.Contains 1 CS domain.

Sequence caution: The sequence AAH17789.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Research Articles on CHORDC1

1. Chp-1 and melusin can interact with cochaperones PP5 and Sgt1 and with each other in an ATP-dependent manner

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CHORDC1 antibody

Reference Product	PubMed Publications
CHP antibody	>2 publications with CHORDC1 and CHP

Organs/Tissues associated with anti-CHORDC1 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with CHORDC1 and Muscle
Brain Antibodies	>1 publications with CHORDC1 and Brain