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TMEM158 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646361

Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide (By similarity). More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Tmem158, Polyclonal Antibody
Full Product Name
Tmem158, ID (Tmem158, Mbbp, Ris1, Transmembrane protein 158, 40kD BINP-binding protein, Ras-induced senescence protein 1)
Product Gene Name
Product Synonym Names
Anti -Tmem158, ID (Tmem158, Mbbp, Ris1, Transmembrane protein 158, 40kD BINP-binding protein, Ras-induced senescence protein 1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
30,404 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (45265956..45267814, complement). Location: 3p21.3
3D Structure
ModBase 3D Structure for Q8WZ71
Immunogen
Mouse Tmem158 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-206 amino acids from the Central region of mouse Tmem158.
Applications Tested/Suitable for anti-TMEM158 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-TMEM158 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-TMEM158 antibody

Western Blot analysis in mouse bladder tissue lysates (35ug/lane) using MBS646361. This demonstrates that MBS646361 detected the mouse Tmem158 protein (arrow).
Rabbit Anti-TMEM158 Polyclonal Antibody – Cat# MBS646361

Other Notes

Small volumes of anti-TMEM158 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMEM158 purchase

MBS646361 is an antibody targeting TMEM158. Also known as Tmem158, ID (Tmem158, Mbbp, Ris1, Transmembrane protein 158, 40kD BINP-binding protein, Ras-induced senescence protein 1). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TMEM158. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
TMEM158 protein
NCBI Official Synonym Full Names
transmembrane protein 158 (gene/pseudogene)
NCBI Official Symbol
TMEM158
NCBI Official Synonym Symbols
BBP; RIS1; p40BBP
UniProt Protein Name
Transmembrane protein 158
UniProt Synonym Protein Names
40 kDa BINP-binding protein; p40BBP; Ras-induced senescence protein 1
Protein Family
UniProt Gene Name
TMEM158
UniProt Synonym Gene Names
HBBP; RIS1; p40BBP
UniProt Entry Name
TM158_HUMAN
NCBI Protein Information
transmembrane protein 158; BINP receptor; Ras induced senescence 1; 40 kDa BINP-binding protein; brain specific binding protein; brain injury-derived neurotrophic peptide (BINP) binding protein

NCBI Summary for TMEM158

Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. [provided by RefSeq, Jul 2008]
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UniProt Comments for TMEM158

Function: Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide

By similarity.

Subcellular location: Membrane; Multi-pass membrane protein

Potential.

Induction: Up-regulated during Ras-induced senesence. Ref.1

Post-translational modification: N-glycosylated

By similarity.

Sequence similarities: Belongs to the TMEM158 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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