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PPP1R1C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646376

Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or… More details

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Product Overview

Online Datasheet in PDF
Product Name
PPP1R1C, Polyclonal Antibody
Full Product Name
PPP1R1C, NT (PPP1R1C, Protein phosphatase 1 regulatory subunit 1C, Inhibitor-5 of protein phosphatase 1)
Product Gene Name
Product Synonym Names
Anti -PPP1R1C, NT (PPP1R1C, Protein phosphatase 1 regulatory subunit 1C, Inhibitor-5 of protein phosphatase 1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
12,346 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (182818968..182996109). Location: 2q31.3
OMIM
613240
3D Structure
ModBase 3D Structure for Q8WVI7
Immunogen
PPP1R1C antibody is generated from rabbits immunized with a KLH conjugated synthetic between 49-76 amino acids selected from the N-terminal region of human PPP1R1C.
Applications Tested/Suitable for anti-PPP1R1C antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-PPP1R1C antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-PPP1R1C antibody

PPP1R1C Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PPP1R1C antibody detected the PPP1R1C protein (arrow).
Rabbit Anti-PPP1R1C Polyclonal Antibody – Cat# MBS646376

Other Notes

Small volumes of anti-PPP1R1C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPP1R1C purchase

MBS646376 is an antibody targeting PPP1R1C. Also known as PPP1R1C, NT (PPP1R1C, Protein phosphatase 1 regulatory subunit 1C, Inhibitor-5 of protein phosphatase 1). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP1R1C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
PPP1R1C protein
NCBI Official Synonym Full Names
protein phosphatase 1, regulatory (inhibitor) subunit 1C
NCBI Official Symbol
PPP1R1C
NCBI Official Synonym Symbols
IPP5
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 1C
UniProt Synonym Protein Names
Inhibitor-5 of protein phosphatase 1
UniProt Gene Name
PPP1R1C
UniProt Synonym Gene Names
IPP5
UniProt Entry Name
PPR1C_HUMAN
NCBI Protein Information
protein phosphatase 1 regulatory subunit 1C; PP1 inhibitor protein 5; inhibitor-5 of protein phosphatase 1; protein phosphatase 1 regulatory subunit 1A

NCBI Summary for PPP1R1C

Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010]
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UniProt Comments for PPP1R1C

Function: Inhibitor of protein-phosphatase 1. Promotes cell growth and cell cycle progress at the G1/S transition. May increase cell susceptibility to TNF-induced apoptosis. Ref.4 Ref.5

Subunit structure: Interacts with PPP1CB. Ref.4

Subcellular location: Cytoplasm

By similarity.

Tissue specificity: Expressed in heart, skeletal muscle, liver and testis (at protein level).

Post-translational modification: Phosphorylation of Thr-34 is required for activity.

Sequence similarities: Belongs to the protein phosphatase inhibitor 1 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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