Rabbit Anti-MAPRE2 Polyclonal Antibody – Cat# MBS646445

MAPRE2 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MAPRE2 antibody detected the MAPRE2 protein (arrow).

MAPRE2 Antibody – Rabbit Polyclonal

Name: MAPRE2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS646445
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646445

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MAPRE2, Polyclonal Antibody

Full Product Name

MAPRE2, NT (MAPRE2, RP1, Microtubule-associated protein RP/EB family member 2, APC-binding protein EB2, End-binding protein 2)

Product Gene Name

anti-MAPRE2 antibody

Product Synonym Names

Anti -MAPRE2, NT (MAPRE2, RP1, Microtubule-associated protein RP/EB family member 2, APC-binding protein EB2, End-binding protein 2)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

37,031 Da

OMIM

605789

3D Structure

ModBase 3D Structure for Q15555

Immunogen

MAPRE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human MAPRE2.

Product Categories/Family for anti-MAPRE2 antibody

Antibodies; Abs to Binding Proteins

Applications Tested/Suitable for anti-MAPRE2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-MAPRE2 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-MAPRE2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAPRE2 purchase

MBS646445 is an antibody targeting MAPRE2. Also known as MAPRE2, NT (MAPRE2, RP1, Microtubule-associated protein RP/EB family member 2, APC-binding protein EB2, End-binding protein 2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MAPRE2. It may not necessarily be applicable to this product.

NCBI GI #

49168574

NCBI Accession #

CAG38782.1

UniProt Primary Accession #

Q15555

UniProt Secondary Accession #

Q9UQ33; B2RE21; B3KR39; B7Z2L3; E9PHR3; F5H1V8

NCBI Official Full Name

MAPRE2

UniProt Protein Name

Microtubule-associated protein RP/EB family member 2

UniProt Synonym Protein Names

APC-binding protein EB2; End-binding protein 2

Protein Family

Microtubule-associated protein RP/EB family

UniProt Gene Name

MAPRE2

UniProt Synonym Gene Names

RP1; EB2

UniProt Entry Name

MARE2_HUMAN

UniProt Comments for MAPRE2

Function: May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration

By similarity.

Subunit structure: Interacts with DCTN1. Binds to the C-terminal domain of APC. Binds monomeric and polymerized tubulin. Ref.1 Ref.9 Ref.10

Subcellular location: Cytoplasm › cytoskeleton. Note: Associated with the microtubule network. Accumulates at the plus end of microtubules. Ref.9

Tissue specificity: Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes. Ref.1

Domain: Composed of two functionally independent domains. The N-terminal domain forms a hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.

Sequence similarities: Belongs to the MAPRE family.Contains 1 CH (calponin-homology) domain.Contains 1 EB1 C-terminal domain.

Sequence caution: The sequence BAA83375.1 differs from that shown. Reason: Erroneous initiation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MAPRE2 antibody

Reference Product	PubMed Publications
APC antibody	>2 publications with MAPRE2 and APC
CLASP2 antibody	>1 publications with MAPRE2 and CLASP2

Diseases associated with anti-MAPRE2 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with MAPRE2 and Neoplasms

Organs/Tissues associated with anti-MAPRE2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2 publications with MAPRE2 and Blood
Lung Antibodies	>1 publications with MAPRE2 and Lung
Eye Antibodies	>1 publications with MAPRE2 and Eye
Nerve Antibodies	>1 publications with MAPRE2 and Nerve
Kidney Antibodies	>1 publications with MAPRE2 and Kidney