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STK11IP Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646516

LKB1 (also STK11 and JBS) is a 55kD member of the CAMK Ser/Thr protein kinase family. It is ubiquitously expressed, and considered to be a tumor suppressor. LKB1 is both nuclear and cytoplasmic, and appears to contribute to cell polarization, G1 cell cycle… More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
STK11IP, Polyclonal Antibody
Full Product Name
STK11IP (Serine/Threonine-protein Kinase 11-interacting Protein, LKB1-interacting Protein 1, KIAA1898, LIP1, LKB1IP, STK11IP1)
Product Gene Name
anti-STK11IP antibody
Product Synonym Names
Anti -STK11IP (Serine/Threonine-protein Kinase 11-interacting Protein, LKB1-interacting Protein 1, KIAA1898, LIP1, LKB1IP, STK11IP1)
Immunogen Sequence
MFGSAPQRPV AMTTAQRDSL LWKLAGLLRE SGDVVLSGCS TLSLLTPTLQ QLNHVFELHL GPWGPGQTGF VALPSHPADS PVILQLQFLF DVLQKTLSLK LVHVAGPGPT GPIKIFPFKS LRHLELRGVP LHCLHGLRGI YSQLETLICS RSLQALEELL SACGGDFCSA LPWLALLSAN FSYNALTALD SSLRLLSALR FLNLSHNQVQ DCQGFLMDLC ELHHLDISYN RLHLVPRMGP SGAALGVLIL RGNELRSLHG LEQLRNLRHL DLAYNLLEGH RELSPLWLLA ELRKLYLEGN PLWFHPEHRA ATAQYLSPRA RDAATGFLLD GKVLSLTDFQ THTSLGLSPM GPPLPWPVGS TPETSGGPDL SDSLSSGGVV TQPLLHKVKS RVHVRRASIS EPSDTDPEPG TLNPSPAGWF VQQHPELELM SSFRERFGRN WLQYRSHLEP SGNPLPATPT TSAPSAPPAS SQGPDTAPRP SPPQEEARGP QESPQKMSEE VRAEPQEEEE EKEGKEEKEE GEMVEQGEEE AGEEEEEEQD QKEVEAELCR PLLVCPLEGP EGIRGRECFL RVTSAHLFEV ELQAARTLER LELQSLEAAE IEPEAQAQRS PRPTGSDLLP GAPILSLRFS YICPDRQLRR YLVLEPDAHA AVQELLAVLT PVTNVAREQL GEARDLLLGR FQCLRCGHEF KPEEPRMGLD SEEGWRPLFQ KTESPAVCPN CGSDHVVLLA VSRGTPNRER KQGEQSLAPS PFASPVCHPP GHGDHLDRAK NSPPQAPSTR DHGSWSLSPP PERCGLRSVD HRLRLFLDVE VFSDAQEEFQ CCLKVPVALA GHTGEFMCLV VVSDRRLYLL KVTGEMREPP ASWLQLTLAV PLQDLSGIEL GLAGQSLRLE WAAGAGRCVL LPRDARHCRA FLEELLDVLQ SLPPAWRNCV SATEEEVTPQ HRLWPLLEKD SSLEARQFFY LRAFLVEGPS TCLVSLLLTP STLFLLDEDA AGSPAEPSPP AASGEASEKV PPSGPGPAVR VREQQPLSSL SSVLLYRSAP EDLRLLFYDE VSRLESFWAL RVVCQEQLTA LLAWIREPWE ELFSVGLRTV IQEALALDR
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human STK11IP.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
121,401 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (220462593..220481173). Location: 2q35
OMIM
607172
3D Structure
ModBase 3D Structure for Q8N1F8
Immunogen
Full length human STK11IP, aa1-1099 (AAH34051.1).

Product Categories/Family for anti-STK11IP antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-STK11IP antibody
Western Blot (WB)
Application Notes for anti-STK11IP antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-STK11IP antibody

Western Blot analysis of STK11IP expression in transfected 293T cell line by STK11IP polyclonal antibody. Lane 1: STK11IP transfected lysate (120.89kD). Lane 2: Non-transfected lysate.
Mouse Anti-STK11IP Polyclonal Antibody – Cat# MBS646516

Other Notes

Small volumes of anti-STK11IP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STK11IP purchase

MBS646516 is an antibody targeting STK11IP. Also known as STK11IP (Serine/Threonine-protein Kinase 11-interacting Protein, LKB1-interacting Protein 1, KIAA1898, LIP1, LKB1IP, STK11IP1). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for STK11IP. It may not necessarily be applicable to this product.

NCBI GI #
116235474
NCBI GeneID
114790
NCBI Accession #
NP_443134.2
UniProt Primary Accession #
Q8N1F8
UniProt Secondary Accession #
Q8NAW9; Q8WXE4; Q96CN3; Q96PY9
UniProt Related Accession #
Q8N1F8
GenBank Nucleotide #
NM_052902.2
NCBI Official Full Name
serine/threonine-protein kinase 11-interacting protein
NCBI Official Synonym Full Names
serine/threonine kinase 11 interacting protein
NCBI Official Symbol
STK11IP
NCBI Official Synonym Symbols
LIP1; LKB1IP; STK11IP1
UniProt Protein Name
Serine/threonine-protein kinase 11-interacting protein
UniProt Synonym Protein Names
LKB1-interacting protein 1
Protein Family
Serine/threonine-protein kinase 11-interacting protein
UniProt Gene Name
STK11IP
UniProt Synonym Gene Names
KIAA1898; LIP1; LKB1IP; STK11IP1
UniProt Entry Name
S11IP_HUMAN
NCBI Protein Information
serine/threonine-protein kinase 11-interacting protein; LKB1 interacting protein; STK11 interacting protein; LKB1-interacting protein 1; serine/threonine kinase 11-interacting protein

UniProt Comments for STK11IP

Function: May regulate STK11/LKB1 function by controlling its subcellular localization. Ref.1

Subunit structure: Found in a ternary complex composed of STK11/LKB1, STK11IP and SMAD4. Interacts with STK11/LKB1 and SMAD4. Ref.1

Subcellular location: Cytoplasm. Note: Some cells show granular or punctuate expression. Colocalizes with STK11/LKB1 and SMAD4 in granular or punctuate structures. Ref.1

Miscellaneous: This gene contains a polymorphic substitution resulting in a variant amino acid from Met-1 to Arg-1 compared to the official human genome. However, this variant sequence is in agreement with EST and mRNA sequences.

Sequence similarities: Belongs to the STK11IP family.Contains 8 LRR (leucine-rich) repeats.

Caution: It is uncertain whether Met-1 or Met-12 is the initiator.
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Research Articles on STK11IP

1. LKB1 and LIP1 provide negative control of TGFbeta signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-STK11IP antibody

 Reference Product  PubMed Publications
 STK11 antibody  >9 publications with STK11IP and STK11
 SMAD4 antibody  >3 publications with STK11IP and SMAD4

Pathways associated with anti-STK11IP antibody

 Products by Pathway  Pathway Diagram
 LKB1 Signaling Events Pathway antibodies  LKB1 Signaling Events Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram

Diseases associated with anti-STK11IP antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with STK11IP and Disease Models, Animal

Organs/Tissues associated with anti-STK11IP antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with STK11IP and Bone
 Vascular Antibodies  >1 publications with STK11IP and Vascular
 Intestine Antibodies  >1 publications with STK11IP and Intestine
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