Rabbit Anti-NIR2 Polyclonal Antibody – Cat# MBS646520

NIR2 Antibody – Rabbit Polyclonal

Name: NIR2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS646520
Price: 720 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646520

Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May… More details

$720 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NIR2, Polyclonal Antibody

Full Product Name

NIR2 (Membrane-associated Phosphatidylinositol Transfer Protein 1, Drosophila Retinal Degeneration B Homolog, Phosphatidylinositol Transfer Protein, Membrane-associated 1, PITPnm 1, Pyk2 N-terminal Domain-interacting Receptor 2, NIR-2, PITPNM1, DRES9, PIT

Product Synonym Names

Anti -NIR2 (Membrane-associated Phosphatidylinositol Transfer Protein 1, Drosophila Retinal Degeneration B Homolog, Phosphatidylinositol Transfer Protein, Membrane-associated 1, PITPnm 1, Pyk2 N-terminal Domain-interacting Receptor 2, NIR-2, PITPNM1, DRES9, PIT

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS.

Purity/Purification

Purified
Purified by ammonium sulfate precipitation.

Specificity

Recognizes human NIR2.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Recombinant corresponding to human NIR2.

Product Categories/Family for anti-NIR2 antibody

Antibodies; Abs to Calcium Binding Proteins

Applications Tested/Suitable for anti-NIR2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-NIR2 antibody

Suitable for use in ELISA and Western Blot.

Other Notes

Small volumes of anti-NIR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NIR2 purchase

MBS646520 is an antibody targeting NIR2. Also known as NIR2 (Membrane-associated Phosphatidylinositol Transfer Protein 1, Drosophila Retinal Degeneration B Homolog, Phosphatidylinositol Transfer Protein, Membrane-associated 1, PITPnm 1, Pyk2 N-terminal Domain-interacting Receptor 2, NIR-2, PITPNM1, DRES9, PIT. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NIR2. It may not necessarily be applicable to this product.

NCBI GI #

12667436

NCBI Accession #

AAK01444.1

NCBI Official Full Name

NIR2

UniProt Comments for NIR2

PITPNM1: putatively transfers phosphatidylinositol and phosphatidylcholine between membranes. Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Has higher affinity for the inactive, GDP-bound form of RHOA. Necessary for normal completion of cytokinesis and for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions. Interacts with PIK4CA and with Pyk2 via its C-terminus. Phosphorylated on multiple sites by CDC2 at the onset of mitosis. CDC2-phosphorylated forms may interact with PLK1. Interacts with VAPB. Phosphorylated on threonine residues upon treatment with oleic acid.

Protein type: Cell surface

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: endoplasmic reticulum membrane; membrane; cytoplasm; lipid particle; midbody; cleavage furrow

Molecular Function: metal ion binding; phosphatidylinositol transporter activity

Biological Process: protein transport; phototransduction; phospholipid transport; brain development; lipid metabolic process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.