• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

BIKE Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6465513

MBS6465513 is an antibody targeting BIKE. Also known as BIKE, ID (BMP-2 inducible Protein Kinase, BMP2K, HRIHFB2017) (MaxLight 550). Reactive in Human, Mouse. Host: Rabbit. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BIKE, Polyclonal Antibody
Full Product Name
BIKE, ID (BMP-2 inducible Protein Kinase, BMP2K, HRIHFB2017) (MaxLight 550)
Product Gene Name
anti-BIKE antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein G Affinity Chromatography.
Specificity
Recognizes human BIKE. Species Crossreactivity: mouse.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
129.171
3D Structure
ModBase 3D Structure for Q9NSY1
Immunogen
Synthetic peptide selected from the center region of human BIKE (KLH).
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-BIKE antibody

Antibodies; Protein Kinases
Applications Tested/Suitable for anti-BIKE antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-BIKE antibody
IHC: 1:50-1:100
FLISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.

Product References and Citations for anti-BIKE antibody

1. Kearns, A.E., et al., J. Biol. Chem. 276(45):42213-42218 (2001). 2. Hoffmann, A., et al., Crit. Rev. Eukaryot. Gene Expr. 11(1-3), 23-45 (2001).

Other Notes

Small volumes of anti-BIKE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BIKE. It may not necessarily be applicable to this product.

NCBI GI #
38787935
NCBI GeneID
55589
NCBI Accession #
NP_942595
UniProt Primary Accession #
Q9NSY1
UniProt Related Accession #
Q9NSY1
GenBank Nucleotide #
NP_942595.1
NCBI Official Full Name
BMP-2-inducible protein kinase isoform a
NCBI Official Synonym Full Names
BMP2 inducible kinase
NCBI Official Symbol
BMP2K
NCBI Official Synonym Symbols
BIKE; HRIHFB2017
UniProt Protein Name
BMP-2-inducible protein kinase
Protein Family
BMP-2-inducible protein kinase
UniProt Gene Name
BMP2K
UniProt Synonym Gene Names
BIKE; BIKe
UniProt Entry Name
BMP2K_HUMAN
NCBI Protein Information
BMP-2-inducible protein kinase

NCBI Summary for BIKE

This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for BIKE

BIKE: May be involved in osteoblast differentiation. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, protein; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Other group; NAK family

Chromosomal Location of Human Ortholog: 4q21.21

Cellular Component: nucleoplasm

Molecular Function: protein serine/threonine kinase activity; phosphatase regulator activity; ATP binding

Biological Process: regulation of catalytic activity; regulation of bone mineralization; protein amino acid phosphorylation
Show more

Research Articles on BIKE

1. Results present the first structures of AAK1 and BIKE which reveal that all members of the Numb-associated kinase family share unusual activation segment architecture.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BIKE antibody

 Reference Product  PubMed Publications
 EPS15 antibody  >1 publications with BIKE and EPS15
 NUMB antibody  >1 publications with BIKE and NUMB

Pathways associated with anti-BIKE antibody

 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram

Diseases associated with anti-BIKE antibody

 Disease Name  Pubmed Publications
 Neurobehavioral Manifestations Antibodies  >1 publications with BIKE and Neurobehavioral Manifestations
 Chromosome Aberrations Antibodies  >1 publications with BIKE and Chromosome Aberrations
 Lung Diseases Antibodies  >1 publications with BIKE and Lung Diseases
 Kidney Diseases Antibodies  >1 publications with BIKE and Kidney Diseases

Organs/Tissues associated with anti-BIKE antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >5 publications with BIKE and Bone
 Eye Antibodies  >3 publications with BIKE and Eye
 Kidney Antibodies  >1 publications with BIKE and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000