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C3orf75 (ELP6) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646601

MBS646601 is an antibody targeting ELP6. Also known as C3orf75, CT (C3orf75, ATP1, TMEM103, Elongator complex protein 6 homolog, Angiotonin-transactivated protein 1, Protein TMEM103). Reactive in Human. Host: Rabbit. The function of this protein has not been… More details

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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
C3orf75 (ELP6), Polyclonal Antibody
Full Product Name
C3orf75, CT (C3orf75, ATP1, TMEM103, Elongator complex protein 6 homolog, Angiotonin-transactivated protein 1, Protein TMEM103)
Product Gene Name
Product Synonym Names
Anti -C3orf75, CT (C3orf75, ATP1, TMEM103, Elongator complex protein 6 homolog, Angiotonin-transactivated protein 1, Protein TMEM103)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
29,793 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (47537130..47555199, complement). Location: 3p21.31
OMIM
615020
3D Structure
ModBase 3D Structure for Q0PNE2
Immunogen
C3orf75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human C3orf75.

Product Categories/Family for anti-ELP6 antibody

Applications Tested/Suitable for anti-ELP6 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-ELP6 antibody
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50

Western Blot (WB) of anti-ELP6 antibody

Western blot analysis of C3orf75 Antibody (C-term) in K562 cell line lysates (35ug/lane).C3orf75 (arrow) was detected using the purified Pab.
Rabbit Anti-ELP6 Polyclonal Antibody – Cat# MBS646601

Immunohistochemistry (IHC) of anti-ELP6 antibody

C3orf75 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the C3orf75 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-ELP6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS646601

Flow Cytometry (FC/FACS) of anti-ELP6 antibody

C3orf75 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-ELP6 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS646601

Other Notes

Small volumes of anti-ELP6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ELP6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Chromosome 3 open reading frame 75
NCBI Official Synonym Full Names
elongator acetyltransferase complex subunit 6
NCBI Official Symbol
ELP6
NCBI Official Synonym Symbols
C3orf75; TMEM103
UniProt Protein Name
Elongator complex protein 6
UniProt Synonym Protein Names
Angiotonin-transactivated protein 1; Protein TMEM103
UniProt Gene Name
ELP6
UniProt Synonym Gene Names
ATP1; C3orf75; TMEM103
UniProt Entry Name
ELP6_HUMAN
NCBI Protein Information
elongator complex protein 6; UPF0405 protein C3orf75; transmembrane protein 103; angiotonin-transactivated protein 1; elongator complex protein 6 homolog

UniProt Comments for ELP6

Function: Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration.

Subunit structure: Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, ELP5 and ELP6. Ref.4

Sequence similarities: Belongs to the ELP6 family.

Sequence caution: The sequence AAH00623.1 differs from that shown. Reason: Frameshift at position 256. The sequence AAH14204.1 differs from that shown. Reason: Frameshift at position 256.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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