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SOX11 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646607

The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SOX11, Polyclonal Antibody
Full Product Name
SOX11 (Transcription factor SOX-11)
Product Synonym Names
Anti -SOX11 (Transcription factor SOX-11)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Bovine, Human, Mouse, Porcine, Rat
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SOX11. Species sequence homology: Mouse, rat, porcine and bovine.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-SRLYYSFKNITKQHP, from SOX11, at the internal region of the protein (NP_003099.1).
Applications Tested/Suitable for anti-SOX11 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SOX11 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:2000
Western Blot: 0.3-1ug/ml, Daudi, Jurkat and MOLT4 cell lysates observed on ~65kD bands

Chemiluminescence of anti-SOX11 antibody

Staining of MOLT4 lysate (35ug protein in RIPA buffer) using MBS646607 (0.5ug/ml). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-SOX11 Polyclonal Antibody – Cat# MBS646607

Other Notes

Small volumes of anti-SOX11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SOX11 purchase

MBS646607 is an antibody targeting SOX11. Also known as SOX11 (Transcription factor SOX-11). Reactive in Bovine, Human, Mouse, Porcine, Rat. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for SOX11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
NCBI Official Full Name
SOX11
Protein Family

UniProt Comments for SOX11

SOX11: Probably important in the developing nervous system. May also have a role in tissue modeling during development.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 2p25

Cellular Component: cytoplasm; nucleus

Molecular Function: translation factor activity, nucleic acid binding; transcription factor activity

Biological Process: neural crest cell development; translation; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of lymphocyte proliferation; glial cell proliferation; neuron differentiation; sympathetic nervous system development; regulation of transforming growth factor beta receptor signaling pathway; embryonic digestive tract morphogenesis; positive regulation of cell proliferation; hard palate development; kidney development; oligodendrocyte development; skeletal development; positive regulation of BMP signaling pathway; glial cell development; positive regulation of neurogenesis; transcription, DNA-dependent; positive regulation of hormone secretion; positive regulation of ossification; embryonic skeletal morphogenesis; positive regulation of osteoblast differentiation; limb bud formation; spinal cord development; lens morphogenesis in camera-type eye; positive regulation of transcription from RNA polymerase II promoter; soft palate development; positive regulation of neuron differentiation; neural tube formation

Disease: Mental Retardation, Autosomal Dominant 27
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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