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GTSE1 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646627

GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling… More details

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Product Overview

Online Datasheet in PDF
Product Name
GTSE1, Polyclonal Antibody
Full Product Name
GTSE1 (G2 and S Phase-expressed Protein 1, Protein B99 Homolog)
Product Gene Name
Product Synonym Names
Anti -GTSE1 (G2 and S Phase-expressed Protein 1, Protein B99 Homolog)
Immunogen Sequence
MDDPKKEDIL LLADEKFDFD LSLSSSSANE DDEVFFGPFG HKERCIAASL ELNNPVPEQP PLPTSESPFA WSPLAGEKFV EVYKEAHLLA LHIESSSRNQ AAQAAKPEDP RSQGVERFIQ ESKLKINLFE KEKEMKKSPT SLKRETYYLS DSPLLGPPVG EPRLLASSPA LPSSGAQARL TRAPGPPHSA HALPRESCTA HAASQAATQR KPGTKLLLPR AASVRGRSIP GAAEKPKKEI PASPSRTKIP AEKESHRDVL PDKPAPGAVN VPAAGSHLGQ GKRAIPVPNK LGLKKTLLKA PGSTSNLARK SSSGPVWSGA SSACTSPAVG KAKSSEFASI PANSSRPLSN ISKSGRMGPA MLRPALPAGP VGASSWQAKR VDVSELAAEQ LTAPPSASPT QPQTPEGGGQ WLNSSCAWSE SSQLNKTRSI RRRDSCLNSK TKVMPTPTNQ FKIPKFSIGD SPDSSTPKLS RAQRPQSCTS VGRVTVHSTP VRRSSGPAPQ SLLSARRVSA LPTPASRRCS GLPPMTPKTM PRAVGSPLCV PARRRSSEPR KNSAMRTEPT RESNRKTDSR LVDVSPDRGS PPSRVPQALN FSPEESDSTF SKSTATEVAR EEAKPGGDAA PSEALLVDIK LEPLAVTPDA ASQPLIDLPL IDFCDTPEAH VAVGSESRPL IDLMTNTPDM NKNVAKPSPV VGQLIDLSSP LIQLSPEADK ENVDSPLLKF
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human GTSE1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
76,645 Da
Chromosome Location
Chromosome: 22; NC_000022.10 (46692638..46729596). Location: 22q13.2-q13.3
OMIM
607477
3D Structure
ModBase 3D Structure for Q9NYZ3
Immunogen
Full length human GTSE1, aa1-720 (NP_057510.2).

Product Categories/Family for anti-GTSE1 antibody

Applications Tested/Suitable for anti-GTSE1 antibody
Western Blot (WB)
Application Notes for anti-GTSE1 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-GTSE1 antibody

GTSE1 polyclonal antibody. Western Blot analysis of GTSE1 expression in human colon.
Mouse Anti-GTSE1 Polyclonal Antibody – Cat# MBS646627

Western Blot (WB) of anti-GTSE1 antibody

Western Blot analysis of GTSE1 expression in transfected 293T cell line by GTSE1 polyclonal antibody. Lane 1: GTSE1 transfected lysate (79.2kD). Lane 2: Non-transfected lysate.
Mouse Anti-GTSE1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS646627

Other Notes

Small volumes of anti-GTSE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GTSE1 purchase

MBS646627 is an antibody targeting GTSE1. Also known as GTSE1 (G2 and S Phase-expressed Protein 1, Protein B99 Homolog). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GTSE1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G2 and S phase-expressed protein 1
NCBI Official Synonym Full Names
G-2 and S-phase expressed 1
NCBI Official Symbol
GTSE1
NCBI Official Synonym Symbols
B99
UniProt Protein Name
G2 and S phase-expressed protein 1
UniProt Synonym Protein Names
Protein B99 homolog
UniProt Gene Name
GTSE1
UniProt Synonym Gene Names
GTSE-1
UniProt Entry Name
GTSE1_HUMAN
NCBI Protein Information
G2 and S phase-expressed protein 1; protein B99 homolog

NCBI Summary for GTSE1

The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for GTSE1

Function: May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.

Subcellular location: Cytoplasm › cytoskeleton. Note: Associated with microtubules.

Developmental stage: Expressed in G2/M phase. Not detected in quiescent cells.

Post-translational modification: Phosphorylated in mitosis

By similarity.

Sequence caution: The sequence CAQ09324.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence CAQ10552.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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