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HEBP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646699

The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2… More details

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Product Overview

Online Datasheet in PDF
Product Name
HEBP1, Polyclonal Antibody
Full Product Name
HEBP1, NT (HEBP1, HBP, Heme-binding protein 1, p22HBP)
Product Gene Name
Product Synonym Names
Anti -HEBP1, NT (HEBP1, HBP, Heme-binding protein 1, p22HBP)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Concentration
0.53mg/ml (lot specific)
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
21,097 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (13127798..13153243, complement). Location: 12p13.1
OMIM
605826
3D Structure
ModBase 3D Structure for Q9NRV9
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 5-32 amino acids from the N-terminal region of human HEBP1.
Applications Tested/Suitable for anti-HEBP1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-HEBP1 antibody
Suitable for use in Western Blot and ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Other applications have not been tested.
Optimal dilutions to be determined by researcher.

Western Blot (WB) of anti-HEBP1 antibody

HEBP1 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the HEBP1 antibody detected the HEBP1 protein (arrow).
Rabbit Anti-HEBP1 Polyclonal Antibody – Cat# MBS646699

Other Notes

Small volumes of anti-HEBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HEBP1 purchase

MBS646699 is an antibody targeting HEBP1. Also known as HEBP1, NT (HEBP1, HBP, Heme-binding protein 1, p22HBP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HEBP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
heme-binding protein 1
NCBI Official Synonym Full Names
heme binding protein 1
NCBI Official Symbol
HEBP1
NCBI Official Synonym Symbols
HBP; HEBP
UniProt Protein Name
Heme-binding protein 1
UniProt Synonym Protein Names
p22HBP
Protein Family
UniProt Gene Name
HEBP1
UniProt Synonym Gene Names
HBP
UniProt Entry Name
HEBP1_HUMAN
NCBI Protein Information
heme-binding protein 1; p22HBP

NCBI Summary for HEBP1

The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]
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UniProt Comments for HEBP1

Function: May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities. Ref.2

Subunit structure: Monomer. Ref.2

Subcellular location: Cytoplasm Ref.2.

Domain: Forms a distorted beta-barrel structure, with two helices that are packed against the outer surface of the barrel. Porphyrins are expected to bind to a hydrophobic patch on the outer surface of the beta-barrel structure

By similarity.

Sequence similarities: Belongs to the HEBP family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HEBP1 antibody

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