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CA3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6467004

MBS6467004 is an antibody targeting CA3. Also known as CA3, NT (Carbonic Anhydrase 3, Carbonic Anhydrase III, CA-III, Carbonate Dehydratase III) (MaxLight 490). Reactive in Human, Mouse. Host: Rabbit. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CA3, Polyclonal Antibody
Full Product Name
CA3, NT (Carbonic Anhydrase 3, Carbonic Anhydrase III, CA-III, Carbonate Dehydratase III) (MaxLight 490)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Specificity
Recognizes human CA3. Species Crossreactivity: mouse.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
29.557
OMIM
114750
3D Structure
ModBase 3D Structure for P07451
Immunogen
Synthetic peptide selected from the N-terminal region of human CA3 (KLH).
Conjugate
MaxLight490
Note
Preservative Free

Product Categories/Family for anti-CA3 antibody

Applications Tested/Suitable for anti-CA3 antibody
Western Blot (WB), FLISA
Application Notes for anti-CA3 antibody
WB: 1:50-1:100
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-CA3 antibody

Western blot analysis of CA3 antibody (N-term) in HepG2 cell line lysates (35ug/lane). CA3 (arrow) was detected using the purified Pab.
Rabbit Anti-CA3 Polyclonal Antibody – Cat# MBS6467004

Western Blot (WB) of anti-CA3 antibody

Western blot analysis of CA3 antibody (N-term) in mouse kidney tissue lysates (35ug/lane). CA3 (arrow) was detected using the purified Pab.
Rabbit Anti-CA3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6467004

Product References and Citations for anti-CA3 antibody

1. Du, A.L., Autoimmunity 42(3), 209-215 (2009). 2. Dai, H.Y., Mol. Carcinog. 47(12), 956-963 (2008). 3. Gailly, P., Kidney Int. 74(1), 52-61 (2008).

Other Notes

Small volumes of anti-CA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CA3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
carbonic anhydrase 3
NCBI Official Synonym Full Names
carbonic anhydrase 3
NCBI Official Symbol
CA3
NCBI Official Synonym Symbols
Car3; CAIII
UniProt Protein Name
Carbonic anhydrase 3
UniProt Synonym Protein Names
Carbonate dehydratase III; Carbonic anhydrase III
Protein Family
UniProt Gene Name
CA3
UniProt Synonym Gene Names
CA-III
UniProt Entry Name
CAH3_HUMAN
NCBI Protein Information
carbonic anhydrase 3

NCBI Summary for CA3

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008]
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UniProt Comments for CA3

CA3: Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family.

Protein type: EC 4.2.1.1; Lyase; Energy Metabolism - nitrogen

Chromosomal Location of Human Ortholog: 8q21.2

Cellular Component: cytosol

Molecular Function: carbonate dehydratase activity; zinc ion binding; nickel ion binding

Biological Process: response to ethanol; bicarbonate transport; one-carbon compound metabolic process; response to oxidative stress
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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