Rabbit Anti-RAB26 Polyclonal Antibody – Cat# MBS646744

RAB26 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RAB26 antibody detected the RAB26 protein (arrow).

RAB26 Antibody – Rabbit Polyclonal

Name: RAB26 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS646744
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646744

Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RAB26, Polyclonal Antibody

Full Product Name

RAB26, CT (RAB26, Ras-related protein Rab-26)

Product Gene Name

anti-RAB26 antibody

Product Synonym Names

Anti -RAB26, CT (RAB26, Ras-related protein Rab-26)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

27,900 Da

Chromosome Location

Chromosome: 16; NC_000016.9 (2198145..2204141). Location: 16p13.3

OMIM

605455

3D Structure

ModBase 3D Structure for Q9ULW5

Immunogen

RAB26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-248 amino acids from the C-terminal region of human RAB26.

Product Categories/Family for anti-RAB26 antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins

Applications Tested/Suitable for anti-RAB26 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-RAB26 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-RAB26 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB26 purchase

MBS646744 is an antibody targeting RAB26. Also known as RAB26, CT (RAB26, Ras-related protein Rab-26). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB26. It may not necessarily be applicable to this product.

NCBI GI #

119605958

NCBI GeneID

25837

NCBI Accession #

EAW85552.1

UniProt Primary Accession #

Q9ULW5

UniProt Secondary Accession #

Q3L6K5; Q6NXS7

UniProt Related Accession #

Q9ULW5

NCBI Official Full Name

RAB26, member RAS oncogene family, isoform CRA_c

NCBI Official Synonym Full Names

RAB26, member RAS oncogene family

NCBI Official Symbol

RAB26

NCBI Official Synonym Symbols

V46133

UniProt Protein Name

Ras-related protein Rab-26

Protein Family

Ras-related protein

UniProt Gene Name

RAB26

UniProt Entry Name

RAB26_HUMAN

NCBI Protein Information

ras-related protein Rab-26; Ras-related oncogene protein

NCBI Summary for RAB26

UniProt Comments for RAB26

Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland. Ref.7 Ref.8

Subunit structure: Interacts with RIMS1

By similarity. Interacts with ADRA2B. Ref.8

Subcellular location: Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle › secretory vesicle membrane; Lipid-anchor; Cytoplasmic side

Probable. Note: Not localized at the plasma membrane

By similarity. Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location. Ref.8

Tissue specificity: Predominantly expressed in brain.

Sequence similarities: Belongs to the small GTPase superfamily. Rab family.

Sequence caution: The sequence BAA84707.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Research Articles on RAB26

1. The small GTPase Rab26 regulates the Golgi to cell surface traffic of alpha(2)-adrenergic receptors, likely through a physical interaction.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB26 antibody

Reference Product	PubMed Publications
RPH3AL antibody	>1 publications with RAB26 and RPH3AL
RIMS1 antibody	>1 publications with RAB26 and RIMS1

Diseases associated with anti-RAB26 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>3 publications with RAB26 and Nervous System Diseases
Kidney Diseases Antibodies	>2 publications with RAB26 and Kidney Diseases
Central Nervous System Diseases Antibodies	>1 publications with RAB26 and Central Nervous System Diseases
Seizures Antibodies	>1 publications with RAB26 and Seizures
Hypertension Antibodies	>1 publications with RAB26 and Hypertension

Organs/Tissues associated with anti-RAB26 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with RAB26 and Brain
Kidney Antibodies	>3 publications with RAB26 and Kidney
Bone Antibodies	>1 publications with RAB26 and Bone
Ascites Antibodies	>1 publications with RAB26 and Ascites
Lung Antibodies	>1 publications with RAB26 and Lung
Pancreas Antibodies	>1 publications with RAB26 and Pancreas