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STX5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646748

MBS646748 is an antibody targeting STX5. Also known as STX5, ID (STX5, STX5A, Syntaxin-5). Reactive in Human, Mouse. Host: Rabbit. STX5 mediates endoplasmic reticulum to Golgi transport (By similarity). More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
STX5, Polyclonal Antibody
Full Product Name
STX5, ID (STX5, STX5A, Syntaxin-5)
Product Gene Name
Product Synonym Names
Anti -STX5, ID (STX5, STX5A, Syntaxin-5)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
39,673 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (62574332..62599563, complement). Location: 11q12.3
OMIM
603189
3D Structure
ModBase 3D Structure for Q13190
Immunogen
STX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-209 amino acids from the Central region of human STX5.
Applications Tested/Suitable for anti-STX5 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-STX5 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-STX5 antibody

STX5 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the STX5 antibody detected the STX5 protein (arrow).
Rabbit Anti-STX5 Polyclonal Antibody – Cat# MBS646748

Western Blot (WB) of anti-STX5 antibody

STX5 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the STX5 antibody detected the STX5 protein (arrow).
Rabbit Anti-STX5 Polyclonal Antibody, Western Blot (WB) – Cat# MBS646748

Other Notes

Small volumes of anti-STX5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STX5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
syntaxin-5 isoform 2
NCBI Official Synonym Full Names
syntaxin 5
NCBI Official Symbol
STX5
NCBI Official Synonym Symbols
SED5; STX5A
UniProt Protein Name
Syntaxin-5
Protein Family
UniProt Gene Name
STX5
UniProt Synonym Gene Names
STX5A
UniProt Entry Name
STX5_HUMAN
NCBI Protein Information
syntaxin-5; syntaxin 5A

NCBI Summary for STX5

This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
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UniProt Comments for STX5

Function: Mediates endoplasmic reticulum to Golgi transport

By similarity.

Subunit structure: Part of a ternary complex containing STX5A, NSFL1C and VCP. Identified in a unique SNARE complex composed of the Golgi SNAREs GOSR1, GOSR2, YKT6 and VTI1A

By similarity. Interacts with COG4. Ref.7

Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane protein

By similarity. Golgi apparatus membrane; Single-pass type IV membrane protein

By similarity.

Sequence similarities: Belongs to the syntaxin family.Contains 1 t-SNARE coiled-coil homology domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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