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HOOK1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646758

This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HOOK1, Monoclonal Antibody
Full Product Name
HOOK1 (Protein Hook Homolog 1, h-hook1, hHK1, MGC10642)
Product Synonym Names
Anti -HOOK1 (Protein Hook Homolog 1, h-hook1, hHK1, MGC10642)
Immunogen Sequence
MLLRKQLAEK ERRIEILESE CKVAKFRDYE EKLIVSAWYN KSLAFQKLGM ESRLVSGGGA CSDTGACTPA RSFLAQQRHI TNTRRNLSVK VPATTSD
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1D11
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human HOOK1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Partial recombinant corresponding to aa632-729 from human HOOK1 (NP_056972) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-HOOK1 antibody

Antibodies; Abs to Stem Cell Research
Applications Tested/Suitable for anti-HOOK1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-HOOK1 antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml

Western Blot (WB) of anti-HOOK1 antibody

Western Blot detection against Immunogen (36.78kD).
Mouse Anti-HOOK1 Monoclonal Antibody – Cat# MBS646758

Immunohistochemistry (IHC) of anti-HOOK1 antibody

Immunoperoxidase of monoclonal antibody to HOOK1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3ug/ml].
Mouse Anti-HOOK1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS646758

Other Notes

Small volumes of anti-HOOK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HOOK1 purchase

MBS646758 is an antibody targeting HOOK1. Also known as HOOK1 (Protein Hook Homolog 1, h-hook1, hHK1, MGC10642). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for HOOK1. It may not necessarily be applicable to this product.

NCBI GI #
3005085
NCBI Accession #
AAC09298.1
NCBI Official Full Name
hook1 protein
Protein Family
Protein Hook

UniProt Comments for HOOK1

HOOK1: Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Belongs to the hook family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 1p32.1

Cellular Component: microtubule

Molecular Function: identical protein binding; protein binding; actin binding

Biological Process: protein transport; endosome organization and biogenesis; lysosome organization and biogenesis; early endosome to late endosome transport; multicellular organismal development; endosome to lysosome transport; spermatid development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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