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METTL2B Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646792

Probable S-adenosyl-L-methionine-dependent methyltransferase that mediates 3-methylcytidine modification of some tRNAs. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
METTL2 (METTL2B), Monoclonal Antibody
Full Product Name
METTL2 (METTL2A, Methyltransferase-like Protein 2A, HSPC266, FLJ11350, FLJ12760, PSENIP1)
Product Gene Name
Product Synonym Names
Anti -METTL2 (METTL2A, Methyltransferase-like Protein 2A, HSPC266, FLJ11350, FLJ12760, PSENIP1)
Immunogen Sequence
SQNQNHLKDW FLENKSEVCE CRNNEDGPGL IMEEQHKCSS KSLEHKTQTP PVEENVTQKI SDLEICAD
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2A9
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human METTL2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
43,426 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (128116783..128142978). Location: 7q32.1
3D Structure
ModBase 3D Structure for Q6P1Q9
Immunogen
Partial recombinant corresponding to aa41-109 from human METTL2 (NP_060866) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-METTL2B antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-METTL2B antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-METTL2B antibody

Western Blot detection against Immunogen (33.59kD).
Mouse Anti-METTL2B Monoclonal Antibody – Cat# MBS646792

Testing Data of anti-METTL2B antibody

Detection limit for recombinant GST tagged METTL2B is 0.1ng/ml as a capture antibody.
Mouse Anti-METTL2B Monoclonal Antibody, Testing Data – Cat# MBS646792

Other Notes

Small volumes of anti-METTL2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for METTL2B purchase

MBS646792 is an antibody targeting METTL2B. Also known as METTL2 (METTL2A, Methyltransferase-like Protein 2A, HSPC266, FLJ11350, FLJ12760, PSENIP1). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for METTL2B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
methyltransferase-like protein 2B
NCBI Official Synonym Full Names
methyltransferase like 2B
NCBI Official Symbol
METTL2B
NCBI Official Synonym Symbols
METL; METTL2; METTL2A; PSENIP1
UniProt Protein Name
Methyltransferase-like protein 2B
UniProt Gene Name
METTL2B
UniProt Entry Name
MET2B_HUMAN
NCBI Protein Information
methyltransferase-like protein 2B

NCBI Summary for METTL2B

This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
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UniProt Comments for METTL2B

Function: Probable S-adenosyl-L-methionine-dependent methyltransferase that mediates 3-methylcytidine modification of some tRNAs. Ref.9

Sequence similarities: Belongs to the methyltransferase superfamily. METL family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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