• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

C13ORF3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6469026

MBS6469026 is an antibody targeting C13orf3. Also known as C13orf3, ID (Chromosome 13 Open Reading Frame 3, Spindle And Kinetochore-associated Protein 3, SKA3, C13orf3, RAMA1) (MaxLight 405). Reactive in Human. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C13orf3, Polyclonal Antibody
Full Product Name
C13orf3, ID (Chromosome 13 Open Reading Frame 3, Spindle And Kinetochore-associated Protein 3, SKA3, C13orf3, RAMA1) (MaxLight 405)
Product Gene Name
anti-C13orf3 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human C13orf3.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
43,978 Da
3D Structure
ModBase 3D Structure for Q8IX90
Immunogen
Synthetic peptide selected from the center region of human C13orf3 (KLH).
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-C13orf3 antibody

Antibodies; Nuclear Proteins
Applications Tested/Suitable for anti-C13orf3 antibody
Western Blot (WB), FLISA
Application Notes for anti-C13orf3 antibody
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-C13orf3 antibody

1. Rush, J., et.al., Nat. Biotechnol. 23(1), 94-101 (2005).

Other Notes

Small volumes of anti-C13orf3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for C13orf3. It may not necessarily be applicable to this product.

NCBI GI #
156523260
NCBI GeneID
221150
NCBI Accession #
NP_659498.3
UniProt Primary Accession #
Q8IX90
UniProt Secondary Accession #
Q5VZV5; Q86WR2; Q8NBG1; Q96D22; A2A330; A2A331; B2RBY2
UniProt Related Accession #
Q8IX90
GenBank Nucleotide #
NM_145061.4
NCBI Official Full Name
SKA3
NCBI Official Synonym Full Names
spindle and kinetochore associated complex subunit 3
NCBI Official Symbol
SKA3
NCBI Official Synonym Symbols
RAMA1; C13orf3
UniProt Protein Name
Spindle and kinetochore-associated protein 3
UniProt Gene Name
SKA3
UniProt Synonym Gene Names
C13orf3; RAMA1
UniProt Entry Name
SKA3_HUMAN
NCBI Protein Information
spindle and kinetochore-associated protein 3

NCBI Summary for C13orf3

This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Show more

UniProt Comments for C13orf3

RAMA1: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization. Belongs to the SKA3 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 13q12.11

Cellular Component: spindle microtubule; cytoplasm; outer kinetochore of condensed chromosome

Molecular Function: protein binding

Biological Process: mitosis; cell division; regulation of microtubule polymerization or depolymerization; chromosome segregation
Show more

Research Articles on C13orf3

1. over-expression of GNL3 and SKA3 in the PC-3 human prostate cancer cell line decreased in vitro cell migration and invasion

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-C13orf3 antibody

 Disease Name  Pubmed Publications
 Neoplasm Invasiveness Antibodies  >1 publications with C13orf3 and Neoplasm Invasiveness
 Breast Neoplasms Antibodies  >1 publications with C13orf3 and Breast Neoplasms
 Disease Models, Animal Antibodies  >1 publications with C13orf3 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >1 publications with C13orf3 and Neoplasm Metastasis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000