Rabbit Anti-CABP4 Polyclonal Antibody – Cat# MBS646922

CABP4 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CABP4 antibody detected the CABP4 protein (arrow).

CABP4 Antibody – Rabbit Polyclonal

Name: CABP4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS646922
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646922

This gene encodes a member of the CABP family of calcium binding protein characterized by four EF-hand motifs. Mutations in this gene are associated with congenital stationary night blindness type 2B. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CABP4, Polyclonal Antibody

Full Product Name

CABP4, CT (CABP4, Calcium-binding protein 4)

Product Gene Name

anti-CABP4 antibody

Product Synonym Names

Anti -CABP4, CT (CABP4, Calcium-binding protein 4)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

30,433 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (67219886..67229245). Location: 11q13.2

OMIM

608965

3D Structure

ModBase 3D Structure for P57796

Immunogen

CABP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the C-terminal region of human CABP4.

Product Categories/Family for anti-CABP4 antibody

Antibodies; Abs to Calcium Binding Proteins

Applications Tested/Suitable for anti-CABP4 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-CABP4 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-CABP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CABP4 purchase

MBS646922 is an antibody targeting CABP4. Also known as CABP4, CT (CABP4, Calcium-binding protein 4). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CABP4. It may not necessarily be applicable to this product.

NCBI GI #

21624641

NCBI GeneID

57010

NCBI Accession #

NP_660201.1

UniProt Primary Accession #

P57796

UniProt Secondary Accession #

Q8N4Z2; Q8WWY5

UniProt Related Accession #

P57796

GenBank Nucleotide #

NM_145200.3

NCBI Official Full Name

calcium-binding protein 4

NCBI Official Synonym Full Names

calcium binding protein 4

NCBI Official Symbol

CABP4

NCBI Official Synonym Symbols

CSNB2B

UniProt Protein Name

Calcium-binding protein 4

Protein Family

Calcium-binding protein

UniProt Gene Name

CABP4

UniProt Synonym Gene Names

CaBP4

UniProt Entry Name

CABP4_HUMAN

NCBI Protein Information

calcium-binding protein 4

UniProt Comments for CABP4

Function: Involved in normal synaptic function through regulation of Ca2+ influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages

By similarity.

Subunit structure: Interacts with CACNA1F and CACNA1D (via IQ domain) in a calcium independent manner

By similarity. Interacts (via N-terminus) with UNC119

By similarity.

Subcellular location: Cytoplasm. Note: Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors

By similarity. Ref.5

Tissue specificity: Expressed in retina and in the inner hair cells (IHC) of the cochlea.

Post-translational modification: Phosphorylated. Phosphorylation levels change with the light conditions and regulate the activity

By similarity.

Involvement in disease: Night blindness, congenital stationary, 2B (CSNB2B) [MIM:610427]: A non-progressive retinal disorder characterized by impaired night vision, often associated with nystagmus and myopia.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.6

Sequence similarities: Contains 4 EF-hand domains.

Research Articles on CABP4

1. Complex regulation of voltage-dependent activation and inactivation properties of retinal voltage-gated Cav1.4 L-type Ca2+ channels by Ca2+-binding protein 4 (CaBP4).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CABP4 antibody

Reference Product	PubMed Publications
CACNA1F antibody	>6 publications with CABP4 and CACNA1F
NYX antibody	>2 publications with CABP4 and NYX
GRM6 antibody	>2 publications with CABP4 and GRM6
KCNV2 antibody	>1 publications with CABP4 and KCNV2
CACNA2D4 antibody	>1 publications with CABP4 and CACNA2D4
UNC119 antibody	>1 publications with CABP4 and UNC119

Diseases associated with anti-CABP4 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>1 publications with CABP4 and Nervous System Diseases
NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B Antibodies	>1 publications with CABP4 and NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B

Organs/Tissues associated with anti-CABP4 antibody

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>10 publications with CABP4 and Eye
Liver Antibodies	>2 publications with CABP4 and Liver
Kidney Antibodies	>1 publications with CABP4 and Kidney
Brain Antibodies	>1 publications with CABP4 and Brain