Mouse Anti-GMPR2 Polyclonal Antibody – Cat# MBS646958

Western Blot analysis of GMPR2 expression in transfected 293T cell line by GMPR2 polyclonal antibody. Lane 1: GMPR2 transfected lysate (38.28kD). Lane 2: Non-transfected lysate.

GMPR2 Antibody – Mouse Polyclonal

Name: GMPR2 Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS646958
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646958

Catalyzes the irreversible NADPH dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role… More details

$880 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GMPR2, Polyclonal Antibody

Full Product Name

GMPR2 (GMP Reductase 2, Guanosine 5'-monophosphate Oxidoreductase 2, Guanosine Monophosphate Reductase 2)

Product Gene Name

anti-GMPR2 antibody

Product Synonym Names

Anti -GMPR2 (GMP Reductase 2, Guanosine 5'-monophosphate Oxidoreductase 2, Guanosine Monophosphate Reductase 2)

Immunogen Sequence

MPHIDNDVKL DFKDVLLRPK RSTLKSRSEV DLTRSFSFRN SKQTYSGVPI IAANMDTVGT FEMAKVLCKF SLFTAVHKHY SLVQWQEFAG QNPDCLEHLA ASSGTGSSDF EQLEQILEAI PQVKYICLDV ANGYSEHFVE FVKDVRKRFP QHTIMAGNVV TGEMVEELIL SGADIIKVGI GPGSVCTTRK KTGVGYPQLS AVMECADAAH GLKGHIISDG GCSCPGDVAK AFGAGADFVM LGGMLAGHSE SGGELIERDG KKYKLFYGMS SEMAMKKYAG GVAEYRASEG KTVEVPFKGD VEHTIRDILG GIRSTCTYVG AAKLKELSRR TTFIRVTQQV NPIFSEAC

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human GMPR2.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

37,874 Da

Chromosome Location

Chromosome: 14; NC_000014.8 (24701633..24708448). Location: 14q12

OMIM

610781

3D Structure

ModBase 3D Structure for Q9P2T1

Immunogen

Full length human GMPR2, aa1-348 (NP_001002000.1).

Product Categories/Family for anti-GMPR2 antibody

Antibodies; Abs to Enzymes

Applications Tested/Suitable for anti-GMPR2 antibody

Western Blot (WB)

Application Notes for anti-GMPR2 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-GMPR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GMPR2 purchase

MBS646958 is an antibody targeting GMPR2. Also known as GMPR2 (GMP Reductase 2, Guanosine 5'-monophosphate Oxidoreductase 2, Guanosine Monophosphate Reductase 2). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GMPR2. It may not necessarily be applicable to this product.

NCBI GI #

545688070

NCBI GeneID

51292

NCBI Accession #

NP_001269952.1

UniProt Primary Accession #

Q9P2T1

UniProt Secondary Accession #

Q567T0; Q6IAJ8; D3DS66

UniProt Related Accession #

Q9P2T1

GenBank Nucleotide #

NM_001283023.1

NCBI Official Full Name

GMP reductase 2 isoform 5

NCBI Official Synonym Full Names

guanosine monophosphate reductase 2

NCBI Official Symbol

GMPR2

UniProt Protein Name

GMP reductase 2

UniProt Synonym Protein Names

Guanosine 5'-monophosphate oxidoreductase 2

Protein Family

GMP reductase

UniProt Gene Name

GMPR2

UniProt Synonym Gene Names

Guanosine monophosphate reductase 2

UniProt Entry Name

GMPR2_HUMAN

NCBI Protein Information

GMP reductase 2; guanosine monophosphate reductase isolog; guanosine 5'-monophosphate oxidoreductase 2

UniProt Comments for GMPR2

Function: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation. Ref.1 Ref.2

Catalytic activity: Inosine 5'-phosphate + NH3 + NADP+ = guanosine 5'-phosphate + NADPH.

Tissue specificity: Highly expressed in heart, skeletal muscle, kidney, brain, liver, prostate, spleen, placenta, testis and ovary. Low expression in colon, thymus and peripheral blood leukocytes. Ref.1 Ref.2

Sequence similarities: Belongs to the IMPDH/GMPR family.

Research Articles on GMPR2

1. Loss of expression of GMPR2 and PPARalpha is associated with breast cancer basal phenotype; indicating that they may play a role in carcinogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GMPR2 antibody

Reference Product	PubMed Publications
IMPDH2 antibody	>1 publications with GMPR2 and IMPDH2

Pathways associated with anti-GMPR2 antibody

Products by Pathway	Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Nucleotides Pathway antibodies	Metabolism Of Nucleotides Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Purine Salvage Pathway antibodies	Purine Salvage Pathway Diagram

Diseases associated with anti-GMPR2 antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>1 publications with GMPR2 and Breast Neoplasms
Carcinoma Antibodies	>1 publications with GMPR2 and Carcinoma
Adenocarcinoma Antibodies	>1 publications with GMPR2 and Adenocarcinoma

Organs/Tissues associated with anti-GMPR2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1 publications with GMPR2 and Blood
Brain Antibodies	>1 publications with GMPR2 and Brain