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CARD10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646972

The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CARD10, Polyclonal Antibody
Full Product Name
CARD10, ID (CARD10, CARMA3, Caspase recruitment domain-containing protein 10, CARD-containing MAGUK protein 3)
Product Gene Name
Product Synonym Names
Anti -CARD10, ID (CARD10, CARMA3, Caspase recruitment domain-containing protein 10, CARD-containing MAGUK protein 3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
115,931 Da
Chromosome Location
Chromosome: 22; NC_000022.10 (37886400..37915543, complement). Location: 22q13.1
OMIM
607209
3D Structure
ModBase 3D Structure for Q9BWT7
Immunogen
CARD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 517-546 amino acids from the Central region of human CARD10.
Applications Tested/Suitable for anti-CARD10 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CARD10 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-CARD10 antibody

CARD10 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CARD10 antibody detected the CARD10 protein (arrow).
Rabbit Anti-CARD10 Polyclonal Antibody – Cat# MBS646972

Other Notes

Small volumes of anti-CARD10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CARD10 purchase

MBS646972 is an antibody targeting CARD10. Also known as CARD10, ID (CARD10, CARMA3, Caspase recruitment domain-containing protein 10, CARD-containing MAGUK protein 3). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CARD10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
caspase recruitment domain-containing protein 10
NCBI Official Synonym Full Names
caspase recruitment domain family, member 10
NCBI Official Symbol
CARD10
NCBI Official Synonym Symbols
BIMP1; CARMA3
UniProt Protein Name
Caspase recruitment domain-containing protein 10
UniProt Synonym Protein Names
CARD-containing MAGUK protein 3
UniProt Gene Name
CARD10
UniProt Synonym Gene Names
CARMA3; Carma 3
UniProt Entry Name
CAR10_HUMAN
NCBI Protein Information
caspase recruitment domain-containing protein 10; carma 3; CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; Bcl10 binding protein and activator of NFKB

UniProt Comments for CARD10

Function: Activates NF-kappa-B via BCL10 and IKK.

Subunit structure: CARD10 and BCL10 bind to each other by CARD-CARD interaction. They both participate in a complex with MALT1, where MALT1 binds to BCL10

By similarity.

Subcellular location: Cytoplasm

By similarity.

Tissue specificity: Detected in adult heart, kidney and liver; lower levels in intestine, placenta, muscle and lung. Also found in fetal lung, liver and kidney.

Sequence similarities: Contains 1 CARD domain.

Caution: Supposed to contain a SH3, a PDZ and a guanylate kinase-like domain. But none of these 3 domains are detected by PROSITE, Pfam or SMART.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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