Mouse Anti-WDHD1 Monoclonal Antibody – Cat# MBS647152

Human Kidney (formalin-fixed, paraffin-embedded) stained with WDHD1 antibody at 15ug/ml followed by biotinylated anti-mouse IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.

WDHD1 Antibody – Mouse Monoclonal

Name: WDHD1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS647152
Price: 785 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647152

Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. More details

$785 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

WDHD1, Monoclonal Antibody

Full Product Name

WDHD1, CT (WD Repeat and HMG-box DNA-binding Protein 1, Acidic Nucleoplasmic DNA-binding Protein 1, And-1, AND1)

Product Gene Name

anti-WDHD1 antibody

Product Synonym Names

Anti -WDHD1, CT (WD Repeat and HMG-box DNA-binding Protein 1, Acidic Nucleoplasmic DNA-binding Protein 1, And-1, AND1)

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

20G10

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human WDHD1. Species sequence homology: Mouse.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

125,967 Da

Chromosome Location

Chromosome: 14; NC_000014.8 (55405656..55493819, complement). Location: 14q22.2

OMIM

608126

3D Structure

ModBase 3D Structure for O75717

Immunogen

Recombinant corresponding to human WDHD1 at C-terminal.

Product Categories/Family for anti-WDHD1 antibody

Antibodies; Abs to Proteins

Applications Tested/Suitable for anti-WDHD1 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-WDHD1 antibody

Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 15ug/ml

Other Notes

Small volumes of anti-WDHD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WDHD1 purchase

MBS647152 is an antibody targeting WDHD1. Also known as WDHD1, CT (WD Repeat and HMG-box DNA-binding Protein 1, Acidic Nucleoplasmic DNA-binding Protein 1, And-1, AND1). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for WDHD1. It may not necessarily be applicable to this product.

NCBI GI #

33875654

NCBI GeneID

11169

NCBI Accession #

AAH00622.1

UniProt Primary Accession #

O75717

UniProt Related Accession #

O75717

NCBI Official Full Name

WDHD1 protein, partial

NCBI Official Synonym Full Names

WD repeat and HMG-box DNA binding protein 1

NCBI Official Symbol

WDHD1

NCBI Official Synonym Symbols

CTF4; AND-1; CHTF4

UniProt Protein Name

WD repeat and HMG-box DNA-binding protein 1

UniProt Synonym Protein Names

Acidic nucleoplasmic DNA-binding protein 1

Protein Family

WD repeat and HMG-box DNA-binding protein

UniProt Gene Name

WDHD1

UniProt Synonym Gene Names

AND1; And-1

UniProt Entry Name

WDHD1_HUMAN

NCBI Protein Information

WD repeat and HMG-box DNA-binding protein 1; Acidic nucleoplasmic DNA-binding protein 1; CTF4, chromosome transmission fidelity factor 4 homolog

NCBI Summary for WDHD1

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

UniProt Comments for WDHD1

Function: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Ref.7

Subunit structure: Interacts with the polymerase alpha catalytic subunit POLA1. Interacts with MCM10. Interacts with DNA2. Ref.4 Ref.13

Subcellular location: Nucleus › nucleoplasm

By similarity.

Sequence similarities: Contains 1 HMG box DNA-binding domain.Contains 7 WD repeats.

Research Articles on WDHD1

1. And-1 together with HJURP regulates the assembly of new CENP-A onto centromeres.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-WDHD1 antibody

Reference Product	PubMed Publications
CDC45 antibody	>4 publications with WDHD1 and CDC45
MCM7 antibody	>3 publications with WDHD1 and MCM7
MCM2 antibody	>3 publications with WDHD1 and MCM2
CDC6 antibody	>2 publications with WDHD1 and CDC6
MCM10 antibody	>2 publications with WDHD1 and MCM10

Diseases associated with anti-WDHD1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with WDHD1 and Neoplasms
Lung Neoplasms Antibodies	>1 publications with WDHD1 and Lung Neoplasms
Neoplasms, Experimental Antibodies	>1 publications with WDHD1 and Neoplasms, Experimental

Organs/Tissues associated with anti-WDHD1 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with WDHD1 and Lung