Mouse Anti-GGT5 Polyclonal Antibody – Cat# MBS647334

Western Blot analysis of GGT5 expression in transfected 293T cell line by GGT5 polyclonal antibody. Lane 1: GGTLA1 transfected lysate (64.57kD). Lane 2: Non-transfected lysate.

GGTLA1 (GGT5) Antibody – Mouse Polyclonal

Name: GGT5 Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS647334
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647334

This gene is a member of gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn't convert… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GGTLA1 (GGT5), Polyclonal Antibody

Full Product Name

GGTLA1 (Gamma-glutamyltransferase 5, Gamma-glutamyltranspeptidase 5, GGT 5, GGT5, Gamma-glutamyltransferase-like Activity 1, Gamma-glutamyl Transpeptidase-related Enzyme, GGT-rel)

Product Gene Name

anti-GGT5 antibody

Product Synonym Names

Anti -GGTLA1 (Gamma-glutamyltransferase 5, Gamma-glutamyltranspeptidase 5, GGT 5, GGT5, Gamma-glutamyltransferase-like Activity 1, Gamma-glutamyl Transpeptidase-related Enzyme, GGT-rel)

Immunogen Sequence

MARGYGATVS LVLLGLGLAL AVIVLAVVLS RHQAPCGPQA FAHAAVAADS KVCSDIGRAI LQQQGSPVDA TIAALVCTSV VNPQSMGLGG GVIFTIYNVT TGKVEVINAR ETVPASHAPS LLDQCAQALP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL RGGHVVAPVL SRFLHNSILR PSLQASTLRQ LFFNGTEPLR PQDPLPWPAL ATTLETVATE GVEVFYTGRL GQMLVEDIAK EGSQLTLQDL AKFQPEVVDA LEVPLGDYTL YSPPPPAGGA ILSFILNVLR GFNFSTESMA RPEGRVNVYH HLVETLKFAK GQRWRLGDPR SHPKLQNASR DLLGETLAQL IRQQIDGRGD HQLSHYSLAE AWGHGTGTSH VSVLGEDGSA VAATSTINTP FGAMVYSPRT GIILNNELLD LCERCPRGSG TTPSPAVSGD RVGGAPGRCW PPVPGERSPS SMVPSILINK AQGSKLVIGG AGGELIISAV AQAIMSKLWL GFDLRAAIAA PILHVNSKGC VEYEPNFSQE VQRGLQDRGQ NQTQRPFFLN VVQAVSQEGA CVYAVSDLRK SGEAAGY

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human GGTLA1.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

62,261 Da

Chromosome Location

Chromosome: 22; NC_000022.10 (24615622..24641317, complement). Location: 22q11.23

OMIM

137168

3D Structure

ModBase 3D Structure for P36269

Immunogen

Full length human GGTLA1, aa1-587 (AAH73999.1).

Product Categories/Family for anti-GGT5 antibody

Antibodies; Abs to Enzymes

Applications Tested/Suitable for anti-GGT5 antibody

Western Blot (WB)

Application Notes for anti-GGT5 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-GGT5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GGT5 purchase

MBS647334 is an antibody targeting GGT5. Also known as GGTLA1 (Gamma-glutamyltransferase 5, Gamma-glutamyltranspeptidase 5, GGT 5, GGT5, Gamma-glutamyltransferase-like Activity 1, Gamma-glutamyl Transpeptidase-related Enzyme, GGT-rel). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GGT5. It may not necessarily be applicable to this product.

NCBI GI #

153266907

NCBI GeneID

2687

NCBI Accession #

NP_001093252.1

UniProt Primary Accession #

P36269

UniProt Secondary Accession #

Q53XM9; Q6GMP0; Q96FC1; Q9UFM5

UniProt Related Accession #

P36269

GenBank Nucleotide #

NM_001099782.1

NCBI Official Full Name

gamma-glutamyltransferase 5 isoform c

NCBI Official Synonym Full Names

gamma-glutamyltransferase 5

NCBI Official Symbol

GGT5

NCBI Official Synonym Symbols

GGTLA1; GGT-REL

UniProt Protein Name

Gamma-glutamyltransferase 5

UniProt Synonym Protein Names

Gamma-glutamyl transpeptidase-related enzyme; GGT-rel; Gamma-glutamyltransferase-like activity 1; Gamma-glutamyltranspeptidase 5; Glutathione hydrolase 5 (EC:3.4.19.13); Leukotriene-C4 hydrolase (EC:3.4.19.14)Cleaved into the following 2 chains:Gamma-glutamyltransferase 5 heavy chain; Gamma-glutamyltransferase 5 light chain

Protein Family

Gamma-glutamyltransferase

UniProt Gene Name

GGT5

UniProt Synonym Gene Names

GGTLA1; GGT 5; GGT-rel

UniProt Entry Name

GGT5_HUMAN

NCBI Protein Information

gamma-glutamyltransferase 5; GGT 5; glutathione hydrolase 5; leukotriene-C4 hydrolase; gamma-glutamyl cleaving enzyme; gamma-glutamyltranspeptidase 5; gamma-glutamyltransferase-like activity 1; gamma-glutamyl transpeptidase-related enzyme; gamma-glutamyl transpeptidase-related protein

NCBI Summary for GGT5

This gene is a member of a gene family that encodes gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn't convert synthetic substrates that are commonly used to assay gamma-glutamyl transpeptidase. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for GGT5

Function: Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4).

Catalytic activity: A (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid.Glutathione + H2O = L-cysteinylglycine + L-glutamate.Leukotriene C4 + H2O = leukotriene D4 + L-glutamate.

Pathway: Sulfur metabolism; glutathione metabolism.Lipid metabolism; leukotriene D4 biosynthesis.

Subunit structure: Heterodimer composed of the light and heavy chains. The active site is located in the light chain

By similarity.

Subcellular location: Membrane; Single-pass type II membrane protein

By similarity.

Sequence similarities: Belongs to the gamma-glutamyltransferase family.

Sequence caution: The sequence CAB55910.1 differs from that shown. Reason: Frameshift at position 446.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GGT5 antibody

Products by Pathway	Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
Cyanoamino Acid Metabolism Pathway antibodies	Cyanoamino Acid Metabolism Pathway Diagram
Cyanoamino Acid Metabolism Pathway antibodies	Cyanoamino Acid Metabolism Pathway Diagram
Glutathione Conjugation Pathway antibodies	Glutathione Conjugation Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram

Diseases associated with anti-GGT5 antibody

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>1 publications with GGT5 and Cardiovascular Diseases
Asthma Antibodies	>1 publications with GGT5 and Asthma

Organs/Tissues associated with anti-GGT5 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with GGT5 and Bone
Lung Antibodies	>1 publications with GGT5 and Lung
Connective Tissue Antibodies	>1 publications with GGT5 and Connective Tissue
Uncharacterized Tissue Antibodies	>1 publications with GGT5 and Uncharacterized Tissue