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P2RX3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647379

P2X3 is a subunit in the family of ion channels activated by extracellular ATP. It was cloned from rat dorsal root ganglia. P2X3 has two putative transmembrane domains with intracellular N- and C-termini. It can form homomeric channels and heteromeric… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
P2RX3, Polyclonal Antibody
Full Product Name
P2RX3 (P2X Purinoceptor 3, P2X3, ATP Receptor, Purinergic Receptor)
Product Gene Name
Product Synonym Names
Anti -P2RX3 (P2X Purinoceptor 3, P2X3, ATP Receptor, Purinergic Receptor)
Clonality
Polyclonal
Isotype
IgY
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes rat P2X3. Species Crossreactivity: human and primate.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
44,289 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (57105841..57137549). Location: 11q12
OMIM
600843
3D Structure
ModBase 3D Structure for P56373
Immunogen
VEKQSTDSGAYSIGH, corresponding to aa383-397 from the C-terminus of rat P2X3.

Product Categories/Family for anti-P2RX3 antibody

Applications Tested/Suitable for anti-P2RX3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
Application Notes for anti-P2RX3 antibody
Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry and Immunocytochemistry.
Dilution: Western Blot: 1:1000
Immunohistochemistry: 1:1000
Immunocytochemistry: 1:1000

Other Notes

Small volumes of anti-P2RX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for P2RX3 purchase

MBS647379 is an antibody targeting P2RX3. Also known as P2RX3 (P2X Purinoceptor 3, P2X3, ATP Receptor, Purinergic Receptor). Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for P2RX3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
P2X purinoceptor 3
NCBI Official Synonym Full Names
purinergic receptor P2X, ligand-gated ion channel, 3
NCBI Official Symbol
P2RX3
NCBI Official Synonym Symbols
P2X3
UniProt Protein Name
P2X purinoceptor 3
UniProt Synonym Protein Names
ATP receptor; Purinergic receptor
Protein Family
UniProt Gene Name
P2RX3
UniProt Synonym Gene Names
P2X3
UniProt Entry Name
P2RX3_HUMAN
NCBI Protein Information
P2X purinoceptor 3; ATP receptor; purinoceptor P2X3; P2X receptor, subunit 3; purinergic receptor P2X3

NCBI Summary for P2RX3

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008]
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UniProt Comments for P2RX3

Function: Receptor for ATP that acts as a ligand-gated ion channel.

Subunit structure: Functional P2XRs are organized as homomeric and heteromeric trimers

By similarity.

Subcellular location: Membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the P2X receptor family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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