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EN2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6473824

MBS6473824 is an antibody targeting EN2. Also known as EN2, CT-2 (Homeobox Protein Engrailed-2, Homeobox Protein en-2, Hu-En-2) (MaxLight 650). Reactive in Human. Host: Rabbit. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EN2, Polyclonal Antibody
Full Product Name
EN2, CT-2 (Homeobox Protein Engrailed-2, Homeobox Protein en-2, Hu-En-2) (MaxLight 650)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human EN2.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
34,211 Da
OMIM
131310
3D Structure
ModBase 3D Structure for P19622
Immunogen
Synthetic peptide selected from the C-terminal region of human EN2 (KLH).
Conjugate
MaxLight650
Note
Preservative Free
Applications Tested/Suitable for anti-EN2 antibody
Western Blot (WB), FLISA
Application Notes for anti-EN2 antibody
WB: 1:50-1:100
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-EN2 antibody

1. Poole S.J., Law M.L.Genomics 4:225-231(1989). 2. Benayed R., Gharani N.Am. J. Hum. Genet. 77:851-868(2005).

Other Notes

Small volumes of anti-EN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein engrailed-2
NCBI Official Synonym Full Names
engrailed homeobox 2
NCBI Official Symbol
EN2
UniProt Protein Name
Homeobox protein engrailed-2
Protein Family
UniProt Gene Name
EN2
UniProt Synonym Gene Names
Homeobox protein en-2; Hu-En-2
UniProt Entry Name
HME2_HUMAN
NCBI Protein Information
homeobox protein engrailed-2; hu-En-2; engrailed homolog 2; homeobox protein en-2

NCBI Summary for EN2

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]
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UniProt Comments for EN2

En-2: Genetic variations in EN2 may be associated with susceptibility to autism. Belongs to the engrailed homeobox family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 7q36

Cellular Component: membrane; nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: multicellular organismal development; midbrain development; neuron development; positive regulation of transcription from RNA polymerase II promoter; hindbrain development

Disease: Autism, Susceptibility To, 10
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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