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Endonuclease G (EndoG) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6473854

MBS6473854 is an antibody targeting EndoG. Also known as Endonuclease G (EndoG) (MaxLight 405). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$1050 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Endonuclease G (EndoG), Polyclonal Antibody
Full Product Name
Endonuclease G (EndoG) (MaxLight 405)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human Endonuclease G (EndoG), a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. EndoG is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD (1,2). Species Crossreactivity: mouse and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (30-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
297
Chromosome Location
Chromosome: 9; NC_000009.11 (131580779..131584955). Location: 9q34.1
OMIM
600440
3D Structure
ModBase 3D Structure for Q14249
Immunogen
Synthetic peptide corresponding to aa55-70 of human EndoG (GGPRGPGELAKYGLP).
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-EndoG antibody

Applications Tested/Suitable for anti-EndoG antibody
Western Blot (WB)
Application Notes for anti-EndoG antibody
WB: 1-2ug/ml
Applications are based on unconjugated antibody.

Product References and Citations for anti-EndoG antibody

1. Li, LY, et al. (2001). Nature. 412:95-9 2. Parrish, J, et al. (2001). Nature. 412:90-4.

Other Notes

Small volumes of anti-EndoG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EndoG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endonuclease G, mitochondrial
NCBI Official Synonym Full Names
endonuclease G
NCBI Official Symbol
ENDOG
UniProt Protein Name
Endonuclease G, mitochondrial
Protein Family
UniProt Gene Name
ENDOG
UniProt Synonym Gene Names
Endo G
UniProt Entry Name
NUCG_HUMAN
NCBI Protein Information
endonuclease G, mitochondrial; endo G; mitochondrial endonuclease G

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EndoG antibody

 Reference Product  PubMed Publications
 AIFM1 antibody  >4 publications with EndoG and AIFM1
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