Rabbit Anti-DNAJC24 Polyclonal Antibody – Cat# MBS647398

DNAJC24 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DNAJC24 antibody detected the DNAJC24 protein (arrow).

DNAJC24 Antibody – Rabbit Polyclonal

Name: DNAJC24 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS647398
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647398

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DNAJC24, Polyclonal Antibody

Full Product Name

DNAJC24, ID (DNAJC24, DPH4, ZCSL3, DnaJ homolog subfamily C member 24, CSL-type zinc finger-containing protein 3, DPH4 homolog)

Product Gene Name

anti-DNAJC24 antibody

Product Synonym Names

Anti -DNAJC24, ID (DNAJC24, DPH4, ZCSL3, DnaJ homolog subfamily C member 24, CSL-type zinc finger-containing protein 3, DPH4 homolog)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

17,008 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (31391377..31454382). Location: 11p13

OMIM

611072

3D Structure

ModBase 3D Structure for Q6P3W2

Immunogen

DNAJC24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human DNAJC24.

Product Categories/Family for anti-DNAJC24 antibody

Antibodies; Abs to Transcription Factors; Zinc (Ring) Finger

Applications Tested/Suitable for anti-DNAJC24 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-DNAJC24 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-DNAJC24 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DNAJC24 purchase

MBS647398 is an antibody targeting DNAJC24. Also known as DNAJC24, ID (DNAJC24, DPH4, ZCSL3, DnaJ homolog subfamily C member 24, CSL-type zinc finger-containing protein 3, DPH4 homolog). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAJC24. It may not necessarily be applicable to this product.

NCBI GI #

71052014

NCBI GeneID

120526

NCBI Accession #

AAH36571.1

UniProt Primary Accession #

Q6P3W2

UniProt Secondary Accession #

A8K0V0; B1ALC1

UniProt Related Accession #

Q6P3W2

NCBI Official Full Name

DNAJC24 protein

NCBI Official Synonym Full Names

DnaJ (Hsp40) homolog, subfamily C, member 24

NCBI Official Symbol

DNAJC24

NCBI Official Synonym Symbols

DPH4; JJJ3; ZCSL3

UniProt Protein Name

DnaJ homolog subfamily C member 24

UniProt Synonym Protein Names

CSL-type zinc finger-containing protein 3; Diphthamide biosynthesis protein 4

Protein Family

DnaJ homolog subfamily

UniProt Gene Name

DNAJC24

UniProt Synonym Gene Names

DPH4; ZCSL3

UniProt Entry Name

DJC24_HUMAN

NCBI Protein Information

dnaJ homolog subfamily C member 24; 1700030A21Rik; DPH4, JJJ3 homolog; DPH4 homolog (JJJ3, S. cerevisiae); diphthamide biosynthesis protein 4; zinc finger, CSL-type containing 3; zinc finger, CSL domain containing 3; CSL-type zinc finger-containing protein 3

NCBI Summary for DNAJC24

Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]

UniProt Comments for DNAJC24

Function: Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta). Ref.5 Ref.6

Pathway: Protein modification; peptidyl-diphthamide biosynthesis.

Subunit structure: Monomer and homooligomer. Iron binding promotes oligomerization. Ref.6

Subcellular location: Cytoplasm › cytoskeleton

By similarity.

Domain: The DPH-type zinc finger can also bind iron ions instead of the expected zinc ions (Ref.6).

Sequence similarities: Belongs to the DPH4 family.Contains 1 DPH-type zinc finger.Contains 1 J domain.

Sequence caution: The sequence EAW68245.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Research Articles on DNAJC24

1. immunotoxin resistance is associated with reversible CpG island methylation and silencing of DPH4 gene transcription

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DNAJC24 antibody

Reference Product	PubMed Publications
ELP4 antibody	>1 publications with DNAJC24 and ELP4
IMMP1L antibody	>1 publications with DNAJC24 and IMMP1L
DCDC1 antibody	>1 publications with DNAJC24 and DCDC1

Diseases associated with anti-DNAJC24 antibody

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>1 publications with DNAJC24 and Congenital Abnormalities