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PTCHD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647493

MBS647493 is an antibody targeting PTCHD1. Also known as PTCHD1, ID (PTCHD1, Patched domain-containing protein 1). Reactive in Mouse. Host: Rabbit. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PTCHD1, Polyclonal Antibody
Full Product Name
PTCHD1, ID (PTCHD1, Patched domain-containing protein 1)
Product Gene Name
Product Synonym Names
Anti -PTCHD1, ID (PTCHD1, Patched domain-containing protein 1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
101,341 Da
Chromosome Location
Chromosome: X; NC_000023.10 (23352985..23414918). Location: Xp22.11
OMIM
300828
3D Structure
ModBase 3D Structure for Q96NR3
Immunogen
PTCHD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 618-647 amino acids from the Central region of human PTCHD1.

Product Categories/Family for anti-PTCHD1 antibody

Applications Tested/Suitable for anti-PTCHD1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PTCHD1 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-PTCHD1 antibody

PTCHD1 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the PTCHD1 antibody detected the PTCHD1 protein (arrow).
Rabbit Anti-PTCHD1 Polyclonal Antibody – Cat# MBS647493

Immunohistochemistry (IHC) of anti-PTCHD1 antibody

PTCHD1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTCHD1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-PTCHD1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS647493

Other Notes

Small volumes of anti-PTCHD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTCHD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
patched domain-containing protein 1
NCBI Official Synonym Full Names
patched domain containing 1
NCBI Official Symbol
PTCHD1
UniProt Protein Name
Patched domain-containing protein 1
UniProt Gene Name
PTCHD1
UniProt Entry Name
PTHD1_HUMAN
NCBI Protein Information
patched domain-containing protein 1

NCBI Summary for PTCHD1

This gene encodes a membrane protein with a patched domain. The encoded protein is similar to Drosophila proteins which act as receptors for the morphogen sonic hedgehog. Deletions in this gene, which is located on the X chromosome, are associated with intellectual disability and autism (PMID: 21091464, PMID: 20844286). [provided by RefSeq, Aug 2011]
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UniProt Comments for PTCHD1

Subcellular location: Cell membrane; Multi-pass membrane protein Ref.4.

Tissue specificity: Widely expressed, including in various regions of the brain with highest expression in the gray and white cerebellum, followed by the cerebellar vermis and the pituitary gland. Ref.4

Sequence similarities: Belongs to the patched family.Contains 1 SSD (sterol-sensing) domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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