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ALDH1L2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647502

MBS647502 is an antibody targeting ALDH1L2. Also known as ALDH1L2, CT (ALDH1L2, Mitochondrial 10-formyltetrahydrofolate dehydrogenase, Aldehyde dehydrogenase family 1 member L2). Reactive in Mouse. Host: Rabbit. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ALDH1L2, Polyclonal Antibody
Full Product Name
ALDH1L2, CT (ALDH1L2, Mitochondrial 10-formyltetrahydrofolate dehydrogenase, Aldehyde dehydrogenase family 1 member L2)
Product Gene Name
Product Synonym Names
Anti -ALDH1L2, CT (ALDH1L2, Mitochondrial 10-formyltetrahydrofolate dehydrogenase, Aldehyde dehydrogenase family 1 member L2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
101,746 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (105413562..105478341, complement). Location: 12q23.3
OMIM
613584
3D Structure
ModBase 3D Structure for Q3SY69
Immunogen
ALDH1L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 750-780 amino acids from the C-terminal region of human ALDH1L2.
Applications Tested/Suitable for anti-ALDH1L2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ALDH1L2 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100

Western Blot (WB) of anti-ALDH1L2 antibody

ALDH1L2 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the ALDH1L2 antibody detected the ALDH1L2 protein (arrow).
Rabbit Anti-ALDH1L2 Polyclonal Antibody – Cat# MBS647502

Immunohistochemistry (IHC) of anti-ALDH1L2 antibody

ALDH1L2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ALDH1L2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-ALDH1L2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS647502

Other Notes

Small volumes of anti-ALDH1L2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH1L2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ALDH1L2 protein
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family, member L2
NCBI Official Symbol
ALDH1L2
NCBI Official Synonym Symbols
mtFDH
UniProt Protein Name
Mitochondrial 10-formyltetrahydrofolate dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase family 1 member L2
UniProt Gene Name
ALDH1L2
UniProt Synonym Gene Names
Mitochondrial 10-FTHFDH; mtFDH
UniProt Entry Name
AL1L2_HUMAN
NCBI Protein Information
mitochondrial 10-formyltetrahydrofolate dehydrogenase; mitochondrial 10-FTHFDH; 10-formyltetrahydrofolate dehydrogenase ALDH1L2; aldehyde dehydrogenase family 1 member L2, mitochondrial; probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2

NCBI Summary for ALDH1L2

This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]
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UniProt Comments for ALDH1L2

Catalytic activity: 10-formyltetrahydrofolate + NADP+ + H2O = tetrahydrofolate + CO2 + NADPH.

Subcellular location: Mitochondrion Ref.5.

Tissue specificity: Highly expressed in pancreas, heart, brain and skeletal muscle. Ref.5

Sequence similarities: In the N-terminal section; belongs to the GART family.In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.Contains 1 acyl carrier domain.

Sequence caution: The sequence AAI03936.1 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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