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HOXB5 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647580

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HOXB5, Monoclonal Antibody
Full Product Name
HOXB5 (Homeobox Protein Hox-B5, Homeobox Protein HHO.C10, HOX2A, Homeobox Protein Hox-2A, Homeobox Protein Hu-1)
Product Gene Name
Product Synonym Names
Anti -HOXB5 (Homeobox Protein Hox-B5, Homeobox Protein HHO.C10, HOX2A, Homeobox Protein Hox-2A, Homeobox Protein Hu-1)
Immunogen Sequence
EGQTPQIFPW MRKLHISHDM TGPDGKRART AYTRYQTLEL EKEFHFNRYL TRRRRIEIAH ALCLSERQIK IWFQNRRMKW KKDNKLKSMS LATAGSAF
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3F10
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human HOXB5.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
29,434 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (46668619..46671103, complement). Location: 17q21.3
OMIM
142960
3D Structure
ModBase 3D Structure for P09067
Immunogen
Partial recombinant corresponding to aa170-367 from human HOXB5 (NP_002138.1) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-HOXB5 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-HOXB5 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-HOXB5 antibody

Western Blot detection against Immunogen (36.52kD).
Mouse Anti-HOXB5 Monoclonal Antibody – Cat# MBS647580

Western Blot (WB) of anti-HOXB5 antibody

Western Blot analysis of HOXB5 expression in transfected 293T cell line by HOXB5 monoclonal antibody.|Lane 1: HOXB5 transfected lysate (29.4kD).|Lane 2: Non-transfected lysate.
Mouse Anti-HOXB5 Monoclonal Antibody, Western Blot (WB) – Cat# MBS647580

Testing Data of anti-HOXB5 antibody

Detection limit for recombinant GST tagged HOXB5 is ~0.1ng/ml as a capture antibody.
Mouse Anti-HOXB5 Monoclonal Antibody, Testing Data – Cat# MBS647580

Other Notes

Small volumes of anti-HOXB5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HOXB5 purchase

MBS647580 is an antibody targeting HOXB5. Also known as HOXB5 (Homeobox Protein Hox-B5, Homeobox Protein HHO.C10, HOX2A, Homeobox Protein Hox-2A, Homeobox Protein Hu-1). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for HOXB5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein Hox-B5
NCBI Official Synonym Full Names
homeobox B5
NCBI Official Symbol
HOXB5
NCBI Official Synonym Symbols
HOX2; HU-1; HOX2A; Hox2.1; HHO.C10
UniProt Protein Name
Homeobox protein Hox-B5
UniProt Synonym Protein Names
Homeobox protein HHO.C10; Homeobox protein Hox-2A; Homeobox protein Hu-1
Protein Family
UniProt Gene Name
HOXB5
UniProt Synonym Gene Names
HOX2A
UniProt Entry Name
HXB5_HUMAN
NCBI Protein Information
homeobox protein Hox-B5; homeo box 2A; homeo box B5; homeobox protein Hu-1; homeobox protein Hox-2A; homeobox protein HHO.C10

NCBI Summary for HOXB5

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008]
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UniProt Comments for HOXB5

Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular location: Nucleus.

Tissue specificity: Spinal cord.

Developmental stage: Embryo.

Sequence similarities: Belongs to the Antp homeobox family.Contains 1 homeobox DNA-binding domain.

Sequence caution: The sequence AAA52681.1 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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