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MKRN3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647627

The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MKRN3, Monoclonal Antibody
Full Product Name
MKRN3 (D15S9, RNF63, ZNF127, Probable E3 Ubiquitin-protein Ligase Makorin-3, RING Finger Protein 63, Zinc Finger Protein 127, MGC88288)
Product Gene Name
Product Synonym Names
Anti -MKRN3 (D15S9, RNF63, ZNF127, Probable E3 Ubiquitin-protein Ligase Makorin-3, RING Finger Protein 63, Zinc Finger Protein 127, MGC88288)
Immunogen Sequence
SFSAYWHQLV EPVRMGEGNM LYKSIKKELV VLRLASLLFK RFLSLRDELP FSEDQWDLLH YELEEYFNLI L*
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
2E10
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human MKRN3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
55,645 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (23810454..23820764). Location: 15q11-q13
OMIM
603856
3D Structure
ModBase 3D Structure for Q13064
Immunogen
Partial recombinant corresponding to aa437-508 from human MKRN3 (NP_005655) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-MKRN3 antibody
ELISA (EL/EIA), Immunofluorescence (IF)
Application Notes for anti-MKRN3 antibody
Suitable for use in ELISA and Immunofluorescence.
Dilution: Immunofluorescence: 10ug/ml

Immunofluorescence (IF) of anti-MKRN3 antibody

Immunofluorescence of monoclonal antibody to MKRN3 on HeLa cell . [antibody concentration 10ug/ml]
Mouse Anti-MKRN3 Monoclonal Antibody – Cat# MBS647627

Other Notes

Small volumes of anti-MKRN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MKRN3 purchase

MBS647627 is an antibody targeting MKRN3. Also known as MKRN3 (D15S9, RNF63, ZNF127, Probable E3 Ubiquitin-protein Ligase Makorin-3, RING Finger Protein 63, Zinc Finger Protein 127, MGC88288). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MKRN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
MKRN3 protein
NCBI Official Synonym Full Names
makorin ring finger protein 3
NCBI Official Symbol
MKRN3
NCBI Official Synonym Symbols
CPPB2; D15S9; RNF63; ZFP127; ZNF127
UniProt Protein Name
Probable E3 ubiquitin-protein ligase makorin-3
UniProt Synonym Protein Names
RING finger protein 63; Zinc finger protein 127
UniProt Gene Name
MKRN3
UniProt Synonym Gene Names
D15S9; RNF63; ZNF127
UniProt Entry Name
MKRN3_HUMAN
NCBI Protein Information
probable E3 ubiquitin-protein ligase makorin-3; RING finger protein 63; zinc finger protein 127

NCBI Summary for MKRN3

The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for MKRN3

Function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins

By similarity. Ref.3

Pathway: Protein modification; protein ubiquitination.

Tissue specificity: Ubiquitous. Ref.1

Miscellaneous: Imprinted, expressed from the paternal chromosome only. A deficiency of MKRN3 is not sufficient to cause Prader-Willi syndrome (PWS).

Sequence similarities: Contains 3 C3H1-type zinc fingers.Contains 1 RING-type zinc finger.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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