• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

GNLY Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647757

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNLY, Monoclonal Antibody
Full Product Name
GNLY (LAG2, NKG5, TLA519, Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell Activation Protein 519)
Product Gene Name
Product Synonym Names
Anti -GNLY (LAG2, NKG5, TLA519, Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell Activation Protein 519)
Immunogen Sequence
LAQEGPQGDL LTKTQELGRD YRTCLTIVQK LKKMVDKPTQ RSVSNAATRV CRTGRSRWRD VCRNFMRRYQ SRVTQGLVAG ETAQQICEDL RLCIPSTGPL
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2A6
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human GNLY.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
16,374 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (85921414..85925967). Location: 2p11.2
OMIM
188855
3D Structure
ModBase 3D Structure for P22749
Immunogen
Partial recombinant corresponding to aa46-145 from GNLY (NP_006424) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-GNLY antibody

Applications Tested/Suitable for anti-GNLY antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-GNLY antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-GNLY antibody

Western Blot detection against Immunogen (37.11kD).
Mouse Anti-GNLY Monoclonal Antibody – Cat# MBS647757

Other Notes

Small volumes of anti-GNLY antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNLY purchase

MBS647757 is an antibody targeting GNLY. Also known as GNLY (LAG2, NKG5, TLA519, Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell Activation Protein 519). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GNLY. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
granulysin isoform 519
NCBI Official Synonym Full Names
granulysin
NCBI Official Symbol
GNLY
NCBI Official Synonym Symbols
519; LAG2; NKG5; LAG-2; D2S69E; TLA519
UniProt Protein Name
Granulysin
UniProt Synonym Protein Names
Lymphokine LAG-2; Protein NKG5; T-cell activation protein 519
Protein Family
UniProt Gene Name
GNLY
UniProt Synonym Gene Names
LAG2; NKG5; TLA519
UniProt Entry Name
GNLY_HUMAN
NCBI Protein Information
granulysin; lymphokine LAG-2; lymphocyte-activation gene 2; T-cell activation protein 519; T-lymphocyte activation gene 519

UniProt Comments for GNLY

Function: Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.

Subcellular location: Secreted. Note: Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.

Tissue specificity: Expressed in natural killer and T-cells.

Induction: By T-cell growth factor and IL2/interleukin-2.

Post-translational modification: A 9 kDa form is produced by proteolytic processing of a 15 kDa protein.

Sequence similarities: Contains 1 saposin B-type domain.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000