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OSBPL8 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647817

ORP8 is a member of the oxysterol-binding protein related protein family. In humans, the gene family consists of 12 members, and extensive splice variation increases the number of encoded protein products substantially. The ORPs have been implicated as sterol… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
OSBPL8, Monoclonal Antibody
Full Product Name
OSBPL8 (Oxysterol-binding Protein-related Protein 8, ORP-8, OSBP-related Protein 8, DKFZp686A11164, MGC126578, MGC133203, KIAA1451, ORP8, OSBP10)
Product Gene Name
Product Synonym Names
Anti -OSBPL8 (Oxysterol-binding Protein-related Protein 8, ORP-8, OSBP-related Protein 8, DKFZp686A11164, MGC126578, MGC133203, KIAA1451, ORP8, OSBP10)
Immunogen Sequence
IIRATSESDG RCWMDALELA LKCSSLLKRT MIREGKEHDL SVSSDSTHVT FYGLLRANNL HSGDNFQLND SEIERQHFKD QDMYSDKSDK ENDQEHDESD NEV
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4H6
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human OSBPL8.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
101,196 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (76745577..76953589, complement). Location: 12q14
OMIM
606736
3D Structure
ModBase 3D Structure for Q9BZF1
Immunogen
Partial recombinant corresponding to aa244-347 from human OSBPL8 (NP_065892) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-OSBPL8 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-OSBPL8 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-OSBPL8 antibody

Western Blot detection against Immunogen (37.44kD).
Mouse Anti-OSBPL8 Monoclonal Antibody – Cat# MBS647817

Western Blot (WB) of anti-OSBPL8 antibody

OSBPL8 monoclonal antibody. Western Blot analysis of OSBPL8 expression in Jurkat.
Mouse Anti-OSBPL8 Monoclonal Antibody, Western Blot (WB) – Cat# MBS647817

Testing Data of anti-OSBPL8 antibody

Detection limit for recombinant GST tagged OSBPL8 is 0.3ng/ml as a capture antibody.
Mouse Anti-OSBPL8 Monoclonal Antibody, Testing Data – Cat# MBS647817

Other Notes

Small volumes of anti-OSBPL8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OSBPL8 purchase

MBS647817 is an antibody targeting OSBPL8. Also known as OSBPL8 (Oxysterol-binding Protein-related Protein 8, ORP-8, OSBP-related Protein 8, DKFZp686A11164, MGC126578, MGC133203, KIAA1451, ORP8, OSBP10). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for OSBPL8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
OSBPL8 protein, partial
NCBI Official Synonym Full Names
oxysterol binding protein-like 8
NCBI Official Symbol
OSBPL8
NCBI Official Synonym Symbols
ORP8; MST120; OSBP10; MSTP120
UniProt Protein Name
Oxysterol-binding protein-related protein 8
UniProt Gene Name
OSBPL8
UniProt Synonym Gene Names
KIAA1451; ORP8; OSBP10; ORP-8
UniProt Entry Name
OSBL8_HUMAN
NCBI Protein Information
oxysterol-binding protein-related protein 8; ORP-8; OSBP-related protein 8

NCBI Summary for OSBPL8

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for OSBPL8

Tissue specificity: Widely expressed. Ref.1

Sequence similarities: Belongs to the OSBP family.Contains 1 PH domain.

Sequence caution: The sequence AAG53411.1 differs from that shown. Reason: Frameshift at position 30. The sequence BAA95975.3 differs from that shown. Reason: Erroneous initiation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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