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KRT34 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647887

Type I hair keratin is one of the two types of hair keratin. It is an acidic protein which heterodimerizes with type II hair keratins to form hair and nails. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KRT34, Monoclonal Antibody
Full Product Name
KRT34 (Keratin, Type I Cuticular Ha4, Hair Keratin, Type I Ha4, Keratin-34, K34, HHA4, HKA4, KRTHA4)
Product Gene Name
Product Synonym Names
Anti -KRT34 (Keratin, Type I Cuticular Ha4, Hair Keratin, Type I Ha4, Keratin-34, K34, HHA4, HKA4, KRTHA4)
Immunogen Sequence
SLENTLTESE AHYSSQLSQV QSLITNVESQ LAEIRCDLER QNQEYQVLLD VRARLECEIN TYRSLLESED CKLPCNPCAT TNASGNSCGP CGTSQKGCCN
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3E5
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human KRTHA4.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
49,424 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (39533921..39538636, complement). Location: 17q21.2
OMIM
602763
3D Structure
ModBase 3D Structure for O76011
Immunogen
Partial recombinant corresponding to aa337-436 from human KRTHA4 (NP_066293.2) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-KRT34 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-KRT34 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-KRT34 antibody

Western Blot detection against Immunogen (36.74kD).
Mouse Anti-KRT34 Monoclonal Antibody – Cat# MBS647887

Western Blot (WB) of anti-KRT34 antibody

Western Blot analysis of KRTHA4 expression in transfected 293T cell line by MBS647887.|Lane 1: KRTHA4 transfected lysate (49.4kD).|Lane 2: Non-transfected lysate.
Mouse Anti-KRT34 Monoclonal Antibody, Western Blot (WB) – Cat# MBS647887

Testing Data of anti-KRT34 antibody

Detection limit for recombinant GST tagged KRT34 is 0.1ng/ml as a capture antibody.
Mouse Anti-KRT34 Monoclonal Antibody, Testing Data – Cat# MBS647887

Other Notes

Small volumes of anti-KRT34 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KRT34 purchase

MBS647887 is an antibody targeting KRT34. Also known as KRT34 (Keratin, Type I Cuticular Ha4, Hair Keratin, Type I Ha4, Keratin-34, K34, HHA4, HKA4, KRTHA4). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT34. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
KRT34 protein
NCBI Official Synonym Full Names
keratin 34
NCBI Official Symbol
KRT34
NCBI Official Synonym Symbols
HA4; Ha-4; hHa4; KRTHA4
UniProt Protein Name
Keratin, type I cuticular Ha4
UniProt Synonym Protein Names
Hair keratin, type I Ha4; Keratin-34
Protein Family
UniProt Gene Name
KRT34
UniProt Synonym Gene Names
HHA4; HKA4; KRTHA4; K34
UniProt Entry Name
KRT34_HUMAN
NCBI Protein Information
keratin, type I cuticular Ha4; K34; keratin-34; hard keratin, type I, 4; hair keratin, type I Ha4; keratin, hair, acidic, 4

NCBI Summary for KRT34

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]
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UniProt Comments for KRT34

Tissue specificity: Expressed in the hair follicles. Ref.1

Miscellaneous: There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).

Sequence similarities: Belongs to the intermediate filament family.

Caution: It is uncertain whether Met-1 or Met-43 is the initiator.

Sequence caution: The sequence CAA76386.1 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-KRT34 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >2 publications with KRT34 and Skin
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