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DEFB4A Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647958

Produced from sera of goats pre-immunized with highly pure (>98%) recombinant human BD-2. The antibody was purified by affinity chromatography employing immobilized human BD-2 matrix. More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BD-2 (DEFB4A), Polyclonal Antibody
Full Product Name
BD-2 (Beta-defensin 4A, Beta-defensin 2, hBD-2, Defensin, beta 2, Skin-antimicrobial Peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B)
Product Gene Name
Product Synonym Names
Anti -BD-2 (Beta-defensin 4A, Beta-defensin 2, hBD-2, Defensin, beta 2, Skin-antimicrobial Peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B)
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.02% sodium azide, 50% glycerol.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human BD-2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
7,038 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (7752199..7754237). Location: 8p23.1
OMIM
602215
3D Structure
ModBase 3D Structure for O15263
Immunogen
Recombinant protein corresponding to human BD-2 expressed in E.coli.

Product Categories/Family for anti-DEFB4A antibody

Applications Tested/Suitable for anti-DEFB4A antibody
Western Blot (WB)
Application Notes for anti-DEFB4A antibody
Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-1ug/ml

Other Notes

Small volumes of anti-DEFB4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DEFB4A purchase

MBS647958 is an antibody targeting DEFB4A. Also known as BD-2 (Beta-defensin 4A, Beta-defensin 2, hBD-2, Defensin, beta 2, Skin-antimicrobial Peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for DEFB4A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
beta-defensin 4A
NCBI Official Synonym Full Names
defensin, beta 4A
NCBI Official Symbol
DEFB4A
NCBI Official Synonym Symbols
BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102
UniProt Protein Name
Beta-defensin 4A
UniProt Synonym Protein Names
Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1
Protein Family
UniProt Gene Name
DEFB4A
UniProt Synonym Gene Names
DEFB102; DEFB2; DEFB4; BD-2; hBD-2; SAP1
UniProt Entry Name
DFB4A_HUMAN
NCBI Protein Information
beta-defensin 4A; defensin, beta 2; defensin, beta 4; skin-antimicrobial peptide 1

NCBI Summary for DEFB4A

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]

UniProt Comments for DEFB4A

Function: Has antibacterial activity

Potential.

Subcellular location: Secreted.

Tissue specificity: Expressed in the skin and respiratory tract.

Induction: By inflammation.

Sequence similarities: Belongs to the beta-defensin family. LAP/TAP subfamily.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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