• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CYGB Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648056

Cytoglobin is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress (Trent and Hargrove, 2002… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CYGB, Monoclonal Antibody
Full Product Name
CYGB (STAP, Cytoglobin, Histoglobin, Stellate Cell Activation-associated Protein)
Product Gene Name
Product Synonym Names
Anti -CYGB (STAP, Cytoglobin, Histoglobin, Stellate Cell Activation-associated Protein)
Immunogen Sequence
MEKVPGEMEI ERRERSEELS EAERKAVQAM WARLYASCED VGVAILVRFF VNFPSAKQYF SQFKHMEDPL EMERSPQLRK HACRVMGALN TVVENLHDPD KVSSVLALVG KAHALKHKVE PVYFKILSGV ILEVVAEEFA SDFPPETQRA WAKLRGLIYS HVTAAYKEVG WVQQVPNATT PPATLPSSGP
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1A1
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human CYGB.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
21,405 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (74523430..74533987, complement). Location: 17q25
OMIM
608759
3D Structure
ModBase 3D Structure for Q8WWM9
Immunogen
Full length recombinant corresponding to aa1-191 from human CYGB (AAH29798) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-CYGB antibody

Applications Tested/Suitable for anti-CYGB antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-CYGB antibody
Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry.
Dilution: Immunofluorescence: 10ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml

Western Blot (WB) of anti-CYGB antibody

Western Blot detection against Immunogen (47.01kD).
Mouse Anti-CYGB Monoclonal Antibody – Cat# MBS648056

Western Blot (WB) of anti-CYGB antibody

Western Blot analysis of CYGB expression in transfected 293T cell line by CYGB monoclonal antibody Lane 1: CYGB transfected lysate (21kD).|Lane 2: Non-transfected lysate.
Mouse Anti-CYGB Monoclonal Antibody, Western Blot (WB) – Cat# MBS648056

Immunohistochemistry (IHC) of anti-CYGB antibody

Immunoperoxidase of monoclonal antibody to CYGB on formalin-fixed paraffin-embedded human heart. [antibody concentration 3ug/ml].
Mouse Anti-CYGB Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS648056

Immunofluorescence (IF) of anti-CYGB antibody

Immunofluorescence of monoclonal antibody to CYGB on HeLa cell . [antibody concentration 10ug/ml].
Mouse Anti-CYGB Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS648056

Testing Data of anti-CYGB antibody

Detection limit for recombinant GST tagged CYGB is ~1ng/ml as a capture antibody.
Mouse Anti-CYGB Monoclonal Antibody, Testing Data – Cat# MBS648056

Other Notes

Small volumes of anti-CYGB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYGB purchase

MBS648056 is an antibody targeting CYGB. Also known as CYGB (STAP, Cytoglobin, Histoglobin, Stellate Cell Activation-associated Protein). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CYGB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytoglobin
NCBI Official Synonym Full Names
cytoglobin
NCBI Official Symbol
CYGB
NCBI Official Synonym Symbols
HGB; STAP
UniProt Protein Name
Cytoglobin
UniProt Synonym Protein Names
Histoglobin; HGb; Stellate cell activation-associated protein
Protein Family
UniProt Gene Name
CYGB
UniProt Synonym Gene Names
STAP; HGb
UniProt Entry Name
CYGB_HUMAN
NCBI Protein Information
cytoglobin; histoglobin; stellate cell activation-associated protein

NCBI Summary for CYGB

This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012]
Show more

UniProt Comments for CYGB

Function: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.

Subunit structure: Homodimer; disulfide-linked. Ref.10

Subcellular location: Cytoplasm

By similarity.

Tissue specificity: Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine. Ref.6

Sequence similarities: Belongs to the globin family.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CYGB antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000