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SERPINI2 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648064

The protein encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development,… More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SERPINI2, Polyclonal Antibody
Full Product Name
SERPINI2 (MEPI, Serpin I2, Myoepithelium-derived Serine Protease Inhibitor, Pancpin, Pancreas-specific Protein TSA2004, Peptidase Inhibitor 14, PI-14, PI14)
Product Gene Name
Product Synonym Names
Anti -SERPINI2 (MEPI, Serpin I2, Myoepithelium-derived Serine Protease Inhibitor, Pancpin, Pancreas-specific Protein TSA2004, Peptidase Inhibitor 14, PI-14, PI14)
Immunogen Sequence
MDTIFLWSLL LLFFGSQASR CSAQKNTEFA VDLYQEVSLS HKDNIIFSPL GITLVLEMVQ LGAKGKAQQQ IRQTLKQQET SAGEEFFVLK SFFSAISEKK QEFTFNLANA LYLQEGFTVK EQYLHGNKEF FQSAIKLVDF QDAKACAEMI STWVERKTDG KIKDMFSGEE FGPLTRLVLV NAIYFKGDWK QKFRKEDTQL INFTKKNGST VKIPMMKALL RTKYGYFSES SLNYQVLELS YKGDEFSLII ILPAEGMDIE EVEKLITAQQ ILKWLSEMQE EEVEISLPRF KVEQKVDFKD VLYSLNITEI FSGGCDLSGI TDSSEVYVSQ VTQKVFFEIN EDGSEAATST GIHIPVIMSL AQSQFIANHP FLFIMKHNPT ESILFMGRVT NPDTQEIKGR DLDSL
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human SERPINI2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
46,145 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (167159577..167196732, complement). Location: 3q26.1
OMIM
605587
3D Structure
ModBase 3D Structure for O75830
Immunogen
Full length human SERPINI2, aa1-405 (NP_006208.1).
Applications Tested/Suitable for anti-SERPINI2 antibody
Western Blot (WB)
Application Notes for anti-SERPINI2 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-SERPINI2 antibody

Western Blot analysis of SERPINI2 expression in transfected 293T cell line by SERPINI2 polyclonal antibody. Lane1: SERPINI2 transfected lysate (44.55kD). Lane2: Non-transfected lysate.
Mouse Anti-SERPINI2 Polyclonal Antibody – Cat# MBS648064

Other Notes

Small volumes of anti-SERPINI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SERPINI2 purchase

MBS648064 is an antibody targeting SERPINI2. Also known as SERPINI2 (MEPI, Serpin I2, Myoepithelium-derived Serine Protease Inhibitor, Pancpin, Pancreas-specific Protein TSA2004, Peptidase Inhibitor 14, PI-14, PI14). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SERPINI2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serpin I2 isoform 1
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade I (pancpin), member 2
NCBI Official Symbol
SERPINI2
NCBI Official Synonym Symbols
MEPI; PI14; PANCPIN; TSA2004
UniProt Protein Name
Serpin I2
UniProt Synonym Protein Names
Myoepithelium-derived serine protease inhibitor; Pancpin; Pancreas-specific protein TSA2004; Peptidase inhibitor 14
Protein Family
UniProt Gene Name
SERPINI2
UniProt Synonym Gene Names
MEPI; PI14; PI-14
UniProt Entry Name
SPI2_HUMAN
NCBI Protein Information
serpin I2; protease inhibitor 14; peptidase inhibitor 14; pancreas-specific protein TSA2004; myoepithelium-derived serine protease inhibitor; serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2

NCBI Summary for SERPINI2

The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
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UniProt Comments for SERPINI2

Subcellular location: Secreted

Probable.

Tissue specificity: Expressed in pancreas and adipose tissues. Ref.1

Sequence similarities: Belongs to the serpin family.

Sequence caution: The sequence AAH27859.2 differs from that shown. Reason: Erroneous initiation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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