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PTGDR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648119

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PGD (Ptgdr), Polyclonal Antibody
Full Product Name
PGD, ID (PGD, PGDH, 6-phosphogluconate dehydrogenase, decarboxylating)
Product Gene Name
anti-Ptgdr antibody
Product Synonym Names
Anti -PGD, ID (PGD, PGDH, 6-phosphogluconate dehydrogenase, decarboxylating)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
40,005 Da
Chromosome Location
Chromosome: 14; NC_000080.6 (44851235..44859375, complement). Location: 14 C1; 14 22.59 cM
3D Structure
ModBase 3D Structure for P70263
Immunogen
PGD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-271 amino acids from the Central region of human PGD.

Product Categories/Family for anti-Ptgdr antibody

Antibodies; Abs to Enzymes; Dehydrogenase
Applications Tested/Suitable for anti-Ptgdr antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-Ptgdr antibody
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50

Western Blot (WB) of anti-Ptgdr antibody

PGD Antibody (Center) western blot analysis in 293,MCF-7 cell line lysates (35ug/lane).This demonstrates the PGD antibody detected PGD protein (arrow).
Rabbit Anti-PTGDR Polyclonal Antibody – Cat# MBS648119

Western Blot (WB) of anti-Ptgdr antibody

PGD Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the PGD antibody detected PGD protein (arrow).
Rabbit Anti-PTGDR Polyclonal Antibody, Western Blot (WB) – Cat# MBS648119

Immunohistochemistry (IHC) of anti-Ptgdr antibody

PGD Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PGD Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-PTGDR Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS648119

Flow Cytometry (FC/FACS) of anti-Ptgdr antibody

PGD Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-PTGDR Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS648119

Other Notes

Small volumes of anti-Ptgdr antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ptgdr purchase

MBS648119 is an antibody targeting Ptgdr. Also known as PGD, ID (PGD, PGDH, 6-phosphogluconate dehydrogenase, decarboxylating). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Ptgdr. It may not necessarily be applicable to this product.

NCBI GI #
225543126
NCBI GeneID
19214
NCBI Accession #
NP_032988.3
UniProt Primary Accession #
P70263
UniProt Secondary Accession #
Q8CCM3; A2RSY4
UniProt Related Accession #
P70263
GenBank Nucleotide #
NM_008962.4
NCBI Official Full Name
prostaglandin D2 receptor
NCBI Official Synonym Full Names
prostaglandin D receptor
NCBI Official Symbol
Ptgdr
NCBI Official Synonym Symbols
DP; PGD
UniProt Protein Name
Prostaglandin D2 receptor
UniProt Synonym Protein Names
Prostanoid DP receptor
Protein Family
Prostaglandin D2 receptor
UniProt Gene Name
Ptgdr
UniProt Synonym Gene Names
PGD receptor
UniProt Entry Name
PD2R_MOUSE
NCBI Protein Information
prostaglandin D2 receptor; PGD receptor; PGD2 receptor; prostanoid DP receptor

UniProt Comments for Ptgdr

Function: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein

Potential.

Tissue specificity: Most abundantly expressed in the ileum, followed by lung, stomach and uterus.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
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Research Articles on Ptgdr

1. Data indicate a PLA2G3-lipocalin-type PGD2 synthase (L-PGDS)-PGD2 receptor DP1 loop that drives mast cell maturation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Ptgdr antibody

 Reference Product  PubMed Publications
 Ptger2 antibody  >4 publications with Ptgdr and Ptger2
 Ptgir antibody  >3 publications with Ptgdr and Ptgir
 Adrb2 antibody  >1 publications with Ptgdr and Adrb2
 Npsr1 antibody  >1 publications with Ptgdr and Npsr1

Pathways associated with anti-Ptgdr antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Non-odorant GPCRs Pathway antibodies  Non-odorant GPCRs Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram

Diseases associated with anti-Ptgdr antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with Ptgdr and Inflammation
 Carcinoma Antibodies  >2 publications with Ptgdr and Carcinoma
 Cardiovascular Diseases Antibodies  >2 publications with Ptgdr and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >2 publications with Ptgdr and Disease Models, Animal
 Flushing Antibodies  >1 publications with Ptgdr and Flushing
 Atherosclerosis Antibodies  >1 publications with Ptgdr and Atherosclerosis
 Hyperplasia Antibodies  >1 publications with Ptgdr and Hyperplasia
 Necrosis Antibodies  >1 publications with Ptgdr and Necrosis
 ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 1 Antibodies  >1 publications with Ptgdr and ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 1

Organs/Tissues associated with anti-Ptgdr antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >1 publications with Ptgdr and Embryonic Tissue
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