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HOXC6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648133

This protein belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA,… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
HOXC6, Polyclonal Antibody
Full Product Name
HOXC6, CT (HOXC6, HOX3C, Homeobox protein Hox-C6, Homeobox protein CP25, Homeobox protein HHO.C8, Homeobox protein Hox-3C)
Product Gene Name
anti-HOXC6 antibody
Product Synonym Names
Anti -HOXC6, CT (HOXC6, HOX3C, Homeobox protein Hox-C6, Homeobox protein CP25, Homeobox protein HHO.C8, Homeobox protein Hox-3C)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
26,915 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (54410642..54424607). Location: 12q13.3
OMIM
142972
3D Structure
ModBase 3D Structure for P09630
Immunogen
HOXC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-238 amino acids from the C-terminal region of human HOXC6.

Product Categories/Family for anti-HOXC6 antibody

Antibodies; Abs to Transcription Factors; Zinc; Ring; Homeobox
Applications Tested/Suitable for anti-HOXC6 antibody
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-HOXC6 antibody
Suitable for use in Western Blot, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50

Western Blot (WB) of anti-HOXC6 antibody

HOXC6 Antibody (C-term) western blot analysis in PC-3 cell line lysates (35ug/lane).This demonstrates the HOXC6 antibody detected the HOXC6 protein (arrow).
Rabbit Anti-HOXC6 Polyclonal Antibody – Cat# MBS648133

Flow Cytometry (FC/FACS) of anti-HOXC6 antibody

HOXC6 Antibody (C-term) flow cytometric analysis of U251 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-HOXC6 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS648133

Other Notes

Small volumes of anti-HOXC6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HOXC6 purchase

MBS648133 is an antibody targeting HOXC6. Also known as HOXC6, CT (HOXC6, HOX3C, Homeobox protein Hox-C6, Homeobox protein CP25, Homeobox protein HHO.C8, Homeobox protein Hox-3C). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HOXC6. It may not necessarily be applicable to this product.

NCBI GI #
24497544
NCBI GeneID
3223
NCBI Accession #
NP_710160.1
UniProt Primary Accession #
P09630
UniProt Secondary Accession #
Q6DK09; B2RBV2
UniProt Related Accession #
P09630
GenBank Nucleotide #
NM_153693.4
NCBI Official Full Name
homeobox protein Hox-C6 isoform 2
NCBI Official Synonym Full Names
homeobox C6
NCBI Official Symbol
HOXC6
NCBI Official Synonym Symbols
CP25; HOX3; HOX3C; HHO.C8
UniProt Protein Name
Homeobox protein Hox-C6
UniProt Synonym Protein Names
Homeobox protein CP25; Homeobox protein HHO.C8; Homeobox protein Hox-3C
Protein Family
Homeobox protein
UniProt Gene Name
HOXC6
UniProt Synonym Gene Names
HOX3C
UniProt Entry Name
HXC6_HUMAN
NCBI Protein Information
homeobox protein Hox-C6; homeo box 3C; homeo box C6; homeo box C8 protein; homeobox protein CP25; homeobox protein HHO.C8; homeobox protein Hox-3C

NCBI Summary for HOXC6

This gene belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons. [provided by RefSeq, Jul 2008]
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UniProt Comments for HOXC6

Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular location: Nucleus.

Sequence similarities: Belongs to the Antp homeobox family.Contains 1 homeobox DNA-binding domain.
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Research Articles on HOXC6

1. HOXC6 expression is an important mechanism of chemotherapeutic drug resistance via its regulation of MDR-1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HOXC6 antibody

 Reference Product  PubMed Publications
 HOXC9 antibody  >8 publications with HOXC6 and HOXC9

Diseases associated with anti-HOXC6 antibody

 Disease Name  Pubmed Publications
 Prostatic Diseases Antibodies  >5 publications with HOXC6 and Prostatic Diseases
 Neoplasm Metastasis Antibodies  >4 publications with HOXC6 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >4 publications with HOXC6 and Breast Neoplasms
 Insulin Resistance Antibodies  >1 publications with HOXC6 and Insulin Resistance
 Uterine Cervical Neoplasms Antibodies  >1 publications with HOXC6 and Uterine Cervical Neoplasms
 Precancerous Conditions Antibodies  >1 publications with HOXC6 and Precancerous Conditions
 Ovarian Neoplasms Antibodies  >1 publications with HOXC6 and Ovarian Neoplasms
 Inflammation Antibodies  >1 publications with HOXC6 and Inflammation
 Hypertrophy Antibodies  >1 publications with HOXC6 and Hypertrophy
 Weight Loss Antibodies  >1 publications with HOXC6 and Weight Loss

Organs/Tissues associated with anti-HOXC6 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >18 publications with HOXC6 and Bone
 Embryonic Tissue Antibodies  >16 publications with HOXC6 and Embryonic Tissue
 Connective Tissue Antibodies  >6 publications with HOXC6 and Connective Tissue
 Skin Antibodies  >6 publications with HOXC6 and Skin
 Brain Antibodies  >5 publications with HOXC6 and Brain
 Muscle Antibodies  >4 publications with HOXC6 and Muscle
 Mammary Gland Antibodies  >3 publications with HOXC6 and Mammary Gland
 Lymph Node Antibodies  >3 publications with HOXC6 and Lymph Node
 Nerve Antibodies  >3 publications with HOXC6 and Nerve
 Stomach Antibodies  >2 publications with HOXC6 and Stomach
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