Mouse Anti-NAALADL2 Monoclonal Antibody – Cat# MBS648260

Western Blot detection against Immunogen (37.11kD).

NAALADL2 Antibody – Mouse Monoclonal

Name: NAALADL2 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS648260
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648260

MBS648260 is an antibody targeting NAALADL2. Also known as NAALADL2 (Inactive N-acetylated-alpha-linked Acidic Dipeptidase-like Protein 2, NAALADase L2). Reactive in Human. Host: Mouse. NAALADL2 may be catalytically inactive. More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NAALADL2, Monoclonal Antibody

Full Product Name

NAALADL2 (Inactive N-acetylated-alpha-linked Acidic Dipeptidase-like Protein 2, NAALADase L2)

Product Gene Name

anti-NAALADL2 antibody

Product Synonym Names

Anti -NAALADL2 (Inactive N-acetylated-alpha-linked Acidic Dipeptidase-like Protein 2, NAALADase L2)

Immunogen Sequence

DPKERAPIRI RMLNDILQDM EKSFLVKQAP PGFYRNILYH LDEKTSRFSI LIEAWEHCKP LASNETLQEA LSEVLNSINS AQVYFKAGLD VFKSVLDGKN

Clonality

Monoclonal

Isotype

IgG2a,k

Clone Number

1G5

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human NAALADL2.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

88,682 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (174577095..175523428). Location: 3q26.31

OMIM

608806

3D Structure

ModBase 3D Structure for Q58DX5

Immunogen

Partial recombinant protein corresponding to aa696-796 from human NAALADL2 (NP_996898) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-NAALADL2 antibody

Antibodies; Abs to Enzymes; Peptidase

Applications Tested/Suitable for anti-NAALADL2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-NAALADL2 antibody

Suitable for use in ELISA and Western Blot.

Other Notes

Small volumes of anti-NAALADL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NAALADL2. It may not necessarily be applicable to this product.

NCBI GI #

34785667

NCBI GeneID

254827

NCBI Accession #

AAH57243.1

UniProt Primary Accession #

Q58DX5

UniProt Secondary Accession #

Q658X9; Q6H9J8; Q6H9J9; Q6PG38

UniProt Related Accession #

Q58DX5

NCBI Official Full Name

NAALADL2 protein

NCBI Official Synonym Full Names

N-acetylated alpha-linked acidic dipeptidase-like 2

NCBI Official Symbol

NAALADL2

UniProt Protein Name

Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2

Protein Family

Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein

UniProt Gene Name

NAALADL2

UniProt Synonym Gene Names

NAALADase L2

UniProt Entry Name

NADL2_HUMAN

NCBI Protein Information

inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2; NAALADase L2; N-acetylated alpha-linked acidic dipeptidase 2; glutamate carboxypeptidase II-type non-peptidase homologue

UniProt Comments for NAALADL2

Function: May be catalytically inactive.

Subcellular location: Membrane; Single-pass type II membrane protein

Potential.

Tissue specificity: Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.

Miscellaneous: The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome. However, Ref.1 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.

Sequence similarities: Belongs to the peptidase M28 family. M28B subfamily.

Caution: Although related to the peptidase M28 family, it lacks the conserved zinc-binding and active sites and therefore has probably lost hydrolase activity.

Sequence caution: The sequence CAE54974.2 differs from that shown. Reason: Contaminating sequence at the C-terminus.The sequence CAH56310.1 differs from that shown. Reason: Frameshift at positions 509 and 518.

Research Articles on NAALADL2

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-NAALADL2 antibody

Disease Name	Pubmed Publications
Vasculitis Antibodies	>1 publications with NAALADL2 and Vasculitis
Coronary Disease Antibodies	>1 publications with NAALADL2 and Coronary Disease
Seizures Antibodies	>1 publications with NAALADL2 and Seizures
Cardiovascular Diseases Antibodies	>1 publications with NAALADL2 and Cardiovascular Diseases

Organs/Tissues associated with anti-NAALADL2 antibody

Organ/Tissue Name	Pubmed Publications
Stomach Antibodies	>1 publications with NAALADL2 and Stomach
Kidney Antibodies	>1 publications with NAALADL2 and Kidney