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TNS4 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648342

MBS648342 is an antibody targeting TNS4. Also known as TNS4 (Tensin-4, C-terminal Tensin-like Protein, CTEN, PP14434). Reactive in Human. Host: Mouse. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TNS4, Monoclonal Antibody
Full Product Name
TNS4 (Tensin-4, C-terminal Tensin-like Protein, CTEN, PP14434)
Product Gene Name
Product Synonym Names
Anti -TNS4 (Tensin-4, C-terminal Tensin-like Protein, CTEN, PP14434)
Immunogen Sequence
MGSKASSPHG LGSPLVASPR LEKRLGGLAP QRGSRISVLS ASPVSDVSYM FGSSQSLLHS SNSSHQSSSR SLESPANSSS SLHSLGSVSL CTRPSDFQAP RNPTLTMGQP RTPHSPPLAK EHASSCPPSI TNSMVDIPIV LINGCPEPGS SPPQRTPGHQ NSVQPGAASP SNPCPATRSN SQTLSDAPFT TCPEGPARDM QPTMKFVMDT SKYWFKPNIT REQAIELLRK EEPGAFVIRD SSSYRGSFGL ALKVQEVPAS AQSRPGEDSN DLIRHFLIES SAKGVHLKGA DEEPYFGSLS AFVCQHSIMA LALPCKLTIP QRELGGADGA SDSTDSPASC QKKSAGCHTL YLSSVSVETL TGALAVQKAI STTFERDILP TPTVVHFKVT EQGITLTDVQ RKVFFRRHYP LTTLRFCGMD PEQRKWQKYC KPSWIFGFVA KSQTEPQENV CHLFAEYDMV QPASQVIGLV TALLQDAERM
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
3B8
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human TNS4.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
76,764 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (38632080..38657933, complement). Location: 17q21.2
OMIM
608385
3D Structure
ModBase 3D Structure for Q8IZW8
Immunogen
Full length recombinant corresponding to aa1-481 from human TNS4 (AAH18706) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-TNS4 antibody
ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-TNS4 antibody
Suitable for use in Immunofluorescence, ELISA and Western Blot.
Dilution: Immunofluorescence: 10ug/ml

Western Blot (WB) of anti-TNS4 antibody

Western Blot detection against Immunogen (78.91kD).
Mouse Anti-TNS4 Monoclonal Antibody – Cat# MBS648342

Western Blot (WB) of anti-TNS4 antibody

Western Blot analysis of TNS4 expression in transfected 293T cell line by TNS4 monoclonal antibody|Lane 1: TNS4 transfected lysate (51.8kD).|Lane 2: Non-transfected lysate.
Mouse Anti-TNS4 Monoclonal Antibody, Western Blot (WB) – Cat# MBS648342

Immunofluorescence (IF) of anti-TNS4 antibody

Immunofluorescence of monoclonal antibody to TNS4 on HeLa cell . [antibody concentration 10ug/ml].
Mouse Anti-TNS4 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS648342

Testing Data of anti-TNS4 antibody

Detection limit for recombinant GST tagged TNS4 is ~0.1ng/ml as a capture antibody.
Mouse Anti-TNS4 Monoclonal Antibody, Testing Data – Cat# MBS648342

Other Notes

Small volumes of anti-TNS4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TNS4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
TNS4 protein, partial
NCBI Official Synonym Full Names
tensin 4
NCBI Official Symbol
TNS4
NCBI Official Synonym Symbols
CTEN; PP14434
UniProt Protein Name
Tensin-4
UniProt Synonym Protein Names
C-terminal tensin-like protein
Protein Family
UniProt Gene Name
TNS4
UniProt Synonym Gene Names
CTEN
UniProt Entry Name
TENS4_HUMAN
NCBI Protein Information
tensin-4; C terminal tensin like; C-terminal tensin-like protein

UniProt Comments for TNS4

Function: May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton

By similarity. May promote apoptosis, via its cleavage by caspase-3.

Subunit structure: Binds to actin filaments and interacts with phosphotyrosine-containing proteins

By similarity.

Subcellular location: Cell junction › focal adhesion. Cytoplasm › cytoskeleton Ref.1.

Tissue specificity: Prostate and placenta. Down regulated in prostate cancer. Ref.1

Post-translational modification: Proteolytically cleaved by caspase-3 during apoptosis. Ref.6

Sequence similarities: Contains 1 phosphatase tensin-type domain.Contains 1 SH2 domain.

Sequence caution: The sequence AAQ15257.1 differs from that shown. Reason: Frameshift at positions 85, 296, 472 and 602.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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