Rabbit Anti-GMCL1P1 Polyclonal Antibody – Cat# MBS648586

GMCL1L Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the GMCL1L antibody detected the GMCL1L protein (arrow).

GMCL1P1 Antibody – Rabbit Polyclonal

Name: GMCL1P1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS648586
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648586

GMCL1L is possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity). Probable substrate-specific adapter of an E3 ubiquitin-protein ligase… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GMCL1L (GMCL1P1), Polyclonal Antibody

Full Product Name

GMCL1L, CT (GMCL1P1, GCL, GMCL1L, Putative germ cell-less protein-like 1-like)

Product Gene Name

anti-GMCL1P1 antibody

Product Synonym Names

Anti -GMCL1L, CT (GMCL1P1, GCL, GMCL1L, Putative germ cell-less protein-like 1-like)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

60,201 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (177611511..177614433, complement). Location: 5q35.3

3D Structure

ModBase 3D Structure for Q8NEA9

Immunogen

GMCL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic between 497-524 amino acids selected from the C-terminal region of human GMCL1L.

Product Categories/Family for anti-GMCL1P1 antibody

Antibodies; Abs to Spermatogenesis; Testis Proteins

Applications Tested/Suitable for anti-GMCL1P1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-GMCL1P1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-GMCL1P1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GMCL1P1 purchase

MBS648586 is an antibody targeting GMCL1P1. Also known as GMCL1L, CT (GMCL1P1, GCL, GMCL1L, Putative germ cell-less protein-like 1-like). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GMCL1P1. It may not necessarily be applicable to this product.

NCBI GI #

119574231

NCBI GeneID

64396

NCBI Accession #

EAW53846.1

UniProt Primary Accession #

Q8NEA9

UniProt Secondary Accession #

Q8TC88; Q8TC89; B2RDW6

UniProt Related Accession #

Q8NEA9

NCBI Official Full Name

germ cell-less homolog 1 (Drosophila)-like

NCBI Official Synonym Full Names

germ cell-less, spermatogenesis associated 1 pseudogene 1

NCBI Official Symbol

GMCL1P1

NCBI Official Synonym Symbols

GCL; GMCL2; GMCL1L

UniProt Protein Name

Putative germ cell-less protein-like 1-like

Protein Family

Putative germ cell-less protein

UniProt Gene Name

GMCL1P1

UniProt Synonym Gene Names

GCL; GMCL1L

UniProt Entry Name

GMCLL_HUMAN

NCBI Summary for GMCL1P1

This locus shares a high degree of identity with the multi-exon germ cell-less gene on chromosome 2. Despite its single-exon nature, this chromosome 5 locus contains an open reading frame that could putatively encode a full-length germ cell-less related protein. [provided by RefSeq, Jul 2008]

UniProt Comments for GMCL1P1

Function: Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport

By similarity. Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Ref.3

Pathway: Protein modification; protein ubiquitination.

Subunit structure: Interacts with TMPO-Beta, TSG101 and TFDP2. Interacts with EMD

By similarity. Interacts with CUL3. Ref.3

Subcellular location: Nucleus matrix

By similarity.

Sequence similarities: Contains 1 BTB (POZ) domain.

Research Articles on GMCL1P1

1. microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.