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PKD1L2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648642

May function as an ion-channel regulator. May function as a G-protein-coupled receptor. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PKD1L2, Monoclonal Antibody
Full Product Name
PKD1L2 (Polycystic Kidney Disease Protein 1-like 2, PC1-like 2 Protein, Polycystin-1L2, KIAA1879, PC1L2, DKFZp686J19100, FLJ45333)
Product Gene Name
anti-PKD1L2 antibody
Product Synonym Names
Anti -PKD1L2 (Polycystic Kidney Disease Protein 1-like 2, PC1-like 2 Protein, Polycystin-1L2, KIAA1879, PC1L2, DKFZp686J19100, FLJ45333)
Immunogen Sequence
MGEDSPVAMF SWYLDNTPTE QAEPLPDACR LRGFWPRSLT LLQSNTSTLL LNSSFLQSRG EVIRIRATAL TRHAYGEDTY VISTVPPREV PACTIAPEEG TVLTSFAIFC NASTALGPLE FCFCLESGSC LHCGPEPALP SVYLPLGEEN NDFVLTVVIS ATNRAGDTQQ TQAMAKVALG DTCVEDVAFQ AAVSEKIPTA LQGEGGPEQL LQLAKAVSSM LNQEHESQGS GQSLSIDVRQ KVREHVLGSL SAVTTGLEDV QRVQELAEVL REVTCRSKEL TPSAQGSCMG DSWEGAPPAA HVSHAR
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
3F6
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in ascites fluid.
Purity/Purification
Ascites
Ascites
Specificity
Recognizes human PKD1L2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
272,575 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (81134484..81253975, complement). Location: 16q23.2
OMIM
607894
3D Structure
ModBase 3D Structure for Q7Z442
Immunogen
Full length recombinant corresponding to aa1-307 from human PKD1L2 (AAH14157) with GST tag.

Product Categories/Family for anti-PKD1L2 antibody

Antibodies; Abs to Disease Markers
Applications Tested/Suitable for anti-PKD1L2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-PKD1L2 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-PKD1L2 antibody

Western Blot detection against Immunogen (59.77kD).
Mouse Anti-PKD1L2 Monoclonal Antibody – Cat# MBS648642

Western Blot (WB) of anti-PKD1L2 antibody

PKD1L2 monoclonal antibody, Western Blot analysis of PKD1L2 expression in Hela.
Mouse Anti-PKD1L2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS648642

Other Notes

Small volumes of anti-PKD1L2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PKD1L2 purchase

MBS648642 is an antibody targeting PKD1L2. Also known as PKD1L2 (Polycystic Kidney Disease Protein 1-like 2, PC1-like 2 Protein, Polycystin-1L2, KIAA1879, PC1L2, DKFZp686J19100, FLJ45333). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PKD1L2. It may not necessarily be applicable to this product.

NCBI GI #
116006951
NCBI GeneID
114780
NCBI Accession #
NP_443124.3
UniProt Primary Accession #
Q7Z442
UniProt Secondary Accession #
Q6UEE1; Q6ZN46; Q6ZSP2; Q8N1H9; Q96CL2; Q96Q08
UniProt Related Accession #
Q7Z442
GenBank Nucleotide #
NM_052892.3
NCBI Official Full Name
polycystic kidney disease protein 1-like 2 isoform a
NCBI Official Synonym Full Names
polycystic kidney disease 1-like 2
NCBI Official Symbol
PKD1L2
NCBI Official Synonym Symbols
PC1L2
UniProt Protein Name
Polycystic kidney disease protein 1-like 2
UniProt Synonym Protein Names
PC1-like 2 protein; Polycystin-1L2
Protein Family
Polycystic kidney disease protein
UniProt Gene Name
PKD1L2
UniProt Synonym Gene Names
KIAA1879; PC1L2
UniProt Entry Name
PK1L2_HUMAN
NCBI Protein Information
polycystic kidney disease protein 1-like 2; polycystin-1L2; PC1-like 2 protein

NCBI Summary for PKD1L2

This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
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UniProt Comments for PKD1L2

Function: May function as an ion-channel regulator. May function as a G-protein-coupled receptor. Ref.3

Subunit structure: May interact via its C-terminus with GNAS and GNAI1. Ref.3

Subcellular location: Membrane; Multi-pass membrane protein

Potential.

Tissue specificity: Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney. Ref.1

Developmental stage: Expressed in fetal heart.

Sequence similarities: Belongs to the polycystin family.Contains 1 C-type lectin domain.Contains 1 GPS domain.Contains 1 PLAT domain.Contains 1 REJ domain.Contains 1 SUEL-type lectin domain.

Sequence caution: The sequence AAQ73173.1 differs from that shown. Reason: Frameshift at positions 2113 and 2117. The sequence AAQ73173.1 differs from that shown. Reason: Frameshift at positions 2114 and 2218. The sequence BAB67772.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence BAC05222.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
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Research Articles on PKD1L2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PKD1L2 antibody

 Reference Product  PubMed Publications
 PLAT antibody  >2 publications with PKD1L2 and PLAT
 PKD1L3 antibody  >1 publications with PKD1L2 and PKD1L3

Diseases associated with anti-PKD1L2 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >5 publications with PKD1L2 and Kidney Diseases

Organs/Tissues associated with anti-PKD1L2 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >5 publications with PKD1L2 and Kidney
 Testis Antibodies  >1 publications with PKD1L2 and Testis
 Uncharacterized Tissue Antibodies  >1 publications with PKD1L2 and Uncharacterized Tissue
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