Mouse Anti-ASZ1 Polyclonal Antibody – Cat# MBS648678

Western Blot analysis of ASZ1 expression in transfected 293T cell line by ASZ1 polyclonal antibody. Lane 1: ASZ1 transfected lysate (43.23kD). Lane 2: Non-transfected lysate.

ASZ1 Antibody – Mouse Polyclonal

Name: ASZ1 Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS648678
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648678

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during… More details

$880 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ASZ1, Polyclonal Antibody

Full Product Name

ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain-containing Protein 1, Ankyrin-like Protein 1, Germ Cell-specific Ankyrin, SAM and Basic Leucine Zipper Domain-containing Protein, ALP1, ANKL1, C7orf7, GASZ, MGC26634, Orf3, CT1.19)

Product Gene Name

anti-ASZ1 antibody

Product Synonym Names

Anti -ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain-containing Protein 1, Ankyrin-like Protein 1, Germ Cell-specific Ankyrin, SAM and Basic Leucine Zipper Domain-containing Protein, ALP1, ANKL1, C7orf7, GASZ, MGC26634, Orf3, CT1.19)

Immunogen Sequence

MAASALRGLP VAGGGESSES EDDGWEIGYL DRTSQKLKRL LPIEEKKEKF KKAMTIGDVS LVQELLDSGI SVDSNFQYGW TPLMYAASVA NAELVRVLLD RGANASFEKD KQSILITACS AHGSEEQILK CVELLLSRNA DPNVACRRLM TPIMYAARDG HTQVVALLVA HGAEVNTQDE NGYTALTWAA RQGHKNIVLK LLELGANKML QTKDGKMPSE IAKRNKHHEI FNLLSFTLNP LEGKLQQLTK EDTICKILTT DSDREKDHIF SSYTAFGDLE VFLHGLGLEH MTDLLKERDI TLRHLLTMRE DEFTKNGITS KDQQKILAAL KELQVEEIQF GELSEETKLE ISGDEFLNFL LKLNKQCGHL ITAVQNVITE LPVNSQKVFY KSY

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human ASZ1.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

53,458 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (117003276..117067577, complement). Location: 7q31.2

OMIM

605797

3D Structure

ModBase 3D Structure for Q8WWH4

Immunogen

Full length human ASZ1, aa1-393 (AAH34963.1).

Product Categories/Family for anti-ASZ1 antibody

Antibodies; Abs to Leucine Zipper Proteins

Applications Tested/Suitable for anti-ASZ1 antibody

Western Blot (WB)

Application Notes for anti-ASZ1 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-ASZ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASZ1 purchase

MBS648678 is an antibody targeting ASZ1. Also known as ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain-containing Protein 1, Ankyrin-like Protein 1, Germ Cell-specific Ankyrin, SAM and Basic Leucine Zipper Domain-containing Protein, ALP1, ANKL1, C7orf7, GASZ, MGC26634, Orf3, CT1.19). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ASZ1. It may not necessarily be applicable to this product.

NCBI GI #

219519054

NCBI GeneID

136991

NCBI Accession #

AAI44213.1

UniProt Primary Accession #

Q8WWH4

UniProt Secondary Accession #

A0AV27; A4D0V0

UniProt Related Accession #

Q8WWH4

NCBI Official Full Name

ASZ1 protein

NCBI Official Synonym Full Names

ankyrin repeat, SAM and basic leucine zipper domain containing 1

NCBI Official Symbol

ASZ1

NCBI Official Synonym Symbols

ALP1; GASZ; Orf3; ANKL1; C7orf7; CT1.19

UniProt Protein Name

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

UniProt Synonym Protein Names

Ankyrin-like protein 1; Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein

Protein Family

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein

UniProt Gene Name

ASZ1

UniProt Synonym Gene Names

ALP1; ANKL1; C7orf7; GASZ

UniProt Entry Name

ASZ1_HUMAN

NCBI Protein Information

ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; 4933400N19Rik; ankyrin-like 1; ankyrin-like protein 1; germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein

UniProt Comments for ASZ1

Function: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation

By similarity.

Subunit structure: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1

By similarity.

Subcellular location: Cytoplasm

By similarity. Note: Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs

By similarity.

Tissue specificity: Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary. Ref.1

Sequence similarities: Contains 6 ANK repeats.Contains 1 SAM (sterile alpha motif) domain.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ASZ1 antibody

Disease Name	Pubmed Publications
Infertility, Female Antibodies	>1 publications with ASZ1 and Infertility, Female
Neoplasms Antibodies	>1 publications with ASZ1 and Neoplasms
Infertility, Male Antibodies	>1 publications with ASZ1 and Infertility, Male
Respiratory Tract Diseases Antibodies	>1 publications with ASZ1 and Respiratory Tract Diseases

Organs/Tissues associated with anti-ASZ1 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>2 publications with ASZ1 and Testis