Mouse Anti-CLEC11A Monoclonal Antibody – Cat# MBS648715

CLEC11A Antibody – Mouse Monoclonal

Name: CLEC11A Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS648715
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648715

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its… More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CLEC11A, Monoclonal Antibody

Full Product Name

CLEC11A (CLECSF3, LSLCL, SCGF, C-type Lectin Domain Family 11 Member A, C-type Lectin Superfamily Member 3, Lymphocyte Secreted C-type Lectin, Stem Cell Growth Factor, p47)

Product Gene Name

anti-CLEC11A antibody

Product Synonym Names

Anti -CLEC11A (CLECSF3, LSLCL, SCGF, C-type Lectin Domain Family 11 Member A, C-type Lectin Superfamily Member 3, Lymphocyte Secreted C-type Lectin, Stem Cell Growth Factor, p47)

Immunogen Sequence

PADRQQMEAL TRYLRAALAP YNWPVWLGVH DRRAEGLYLF ENGQRVSFFA WHRSPRPELG AQPSASPHPL SPDQPNGGTL ENCVAQASDD GSWWDHDCQR RLYYVCEFPF *

Clonality

Monoclonal

Isotype

IgG2b lambda

Clone Number

3E1

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human CLEC11A.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap

Molecular Weight

35,695 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (51226588..51228981). Location: 19q13.3

OMIM

604713

3D Structure

ModBase 3D Structure for Q9Y240

Immunogen

Partial recombinant corresponding to aa214-324 from human CLEC11A (NP_002966) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-CLEC11A antibody

Antibodies; Abs to Lectins

Applications Tested/Suitable for anti-CLEC11A antibody

ELISA (EL/EIA)

Application Notes for anti-CLEC11A antibody

Suitable for use in ELISA.

Other Notes

Small volumes of anti-CLEC11A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLEC11A purchase

MBS648715 is an antibody targeting CLEC11A. Also known as CLEC11A (CLECSF3, LSLCL, SCGF, C-type Lectin Domain Family 11 Member A, C-type Lectin Superfamily Member 3, Lymphocyte Secreted C-type Lectin, Stem Cell Growth Factor, p47). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CLEC11A. It may not necessarily be applicable to this product.

NCBI GI #

4506803

NCBI GeneID

6320

NCBI Accession #

NP_002966.1

UniProt Primary Accession #

Q9Y240

UniProt Secondary Accession #

B2RAD4

UniProt Related Accession #

Q9Y240

GenBank Nucleotide #

NM_002975.2

NCBI Official Full Name

C-type lectin domain family 11 member A

NCBI Official Synonym Full Names

C-type lectin domain family 11, member A

NCBI Official Symbol

CLEC11A

NCBI Official Synonym Symbols

P47; SCGF; LSLCL; CLECSF3

UniProt Protein Name

C-type lectin domain family 11 member A

UniProt Synonym Protein Names

C-type lectin superfamily member 3; Lymphocyte secreted C-type lectin; Stem cell growth factor; p47

Protein Family

C-type lectin domain family

UniProt Gene Name

CLEC11A

UniProt Synonym Gene Names

CLECSF3; LSLCL; SCGF

UniProt Entry Name

CLC11_HUMAN

NCBI Protein Information

C-type lectin domain family 11 member A; stem cell growth factor; lymphocyte secreted C-type lectin; C-type lectin superfamily member 3; lymphocyte secreted long form of C-type lectin; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 3

UniProt Comments for CLEC11A

Function: Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation. Ref.7

Subcellular location: Cytoplasm. Secreted Ref.8.

Tissue specificity: Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver. Ref.1 Ref.2 Ref.7 Ref.8

Developmental stage: In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils. Ref.8

Post-translational modification: O-glycosylated. Probably sulfated on the O-glycans. Ref.1

Sequence similarities: Contains 1 C-type lectin domain.

Research Articles on CLEC11A

1. This is the first report of SCGF beta in heart failure patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLEC11A antibody

Reference Product	PubMed Publications
KITLG antibody	>8 publications with CLEC11A and KITLG

Diseases associated with anti-CLEC11A antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>4 publications with CLEC11A and Neoplasms
Anemia Antibodies	>2 publications with CLEC11A and Anemia
Bone Marrow Diseases Antibodies	>1 publications with CLEC11A and Bone Marrow Diseases
Inflammation Antibodies	>1 publications with CLEC11A and Inflammation
Fibrosis Antibodies	>1 publications with CLEC11A and Fibrosis

Organs/Tissues associated with anti-CLEC11A antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>8 publications with CLEC11A and Blood
Bone Marrow Antibodies	>4 publications with CLEC11A and Bone Marrow
Bone Antibodies	>4 publications with CLEC11A and Bone
Embryonic Tissue Antibodies	>2 publications with CLEC11A and Embryonic Tissue
Heart Antibodies	>1 publications with CLEC11A and Heart