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GRPEL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648755

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GRPEL1, Polyclonal Antibody
Full Product Name
GRPEL1, ID (GRPEL1, GREPEL1, GrpE protein homolog 1, mitochondrial, HMGE, Mt-GrpE#1)
Product Gene Name
Product Synonym Names
Anti -GRPEL1, ID (GRPEL1, GREPEL1, GrpE protein homolog 1, mitochondrial, HMGE, Mt-GrpE#1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
24,279 Da
Chromosome Location
Chromosome: 4; NC_000004.11 (7061780..7069800, complement). Location: 4p16
OMIM
606173
3D Structure
ModBase 3D Structure for Q9HAV7
Immunogen
GRPEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-142 amino acids from the Central region of human GRPEL1.
Applications Tested/Suitable for anti-GRPEL1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-GRPEL1 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-GRPEL1 antibody

GRPEL1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the GRPEL1 antibody detected the GRPEL1 protein (arrow).
Rabbit Anti-GRPEL1 Polyclonal Antibody – Cat# MBS648755

Other Notes

Small volumes of anti-GRPEL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GRPEL1 purchase

MBS648755 is an antibody targeting GRPEL1. Also known as GRPEL1, ID (GRPEL1, GREPEL1, GrpE protein homolog 1, mitochondrial, HMGE, Mt-GrpE#1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GRPEL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
grpE protein homolog 1, mitochondrial
NCBI Official Synonym Full Names
GrpE-like 1, mitochondrial (E. coli)
NCBI Official Symbol
GRPEL1
NCBI Official Synonym Symbols
HMGE
UniProt Protein Name
GrpE protein homolog 1, mitochondrial
UniProt Synonym Protein Names
HMGE; Mt-GrpE#1
Protein Family
UniProt Gene Name
GRPEL1
UniProt Synonym Gene Names
GREPEL1
UniProt Entry Name
GRPE1_HUMAN
NCBI Protein Information
grpE protein homolog 1, mitochondrial; mt-GrpE#1; GrpE-like protein cochaperone

UniProt Comments for GRPEL1

Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.

Subunit structure: Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, GRPEL1 or GRPEL2, TIMM44, TIMM16/PAM16 and TIMM14/DNAJC19

By similarity. Binds to HSP70, HSC70 and HSJ1B.

Subcellular location: Mitochondrion matrix.

Sequence similarities: Belongs to the GrpE family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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