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PLBD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648915

Phospholipase acting on various phospholipids including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids. May have a role in the defense against invading microorganisms and in the generation of lipid mediators of… More details

$970 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLBD1, Polyclonal Antibody
Full Product Name
PLBD1 (Phospholipase B-like 1, LAMA-like Protein 1, Lamina Ancestor Homolog 1, Phospholipase B Domain-containing Protein 1, FLJ22662)
Product Gene Name
anti-PLBD1 antibody
Product Synonym Names
Anti -PLBD1 (Phospholipase B-like 1, LAMA-like Protein 1, Lamina Ancestor Homolog 1, Phospholipase B Domain-containing Protein 1, FLJ22662)
Immunogen Sequence
MMADSGKRWA DIFSKYNSGT YNNQYMVLDL KKVKLNHSLD KGTLYIVEQI PTYVEYSEQT DVLRKGYWPS YNVPFHEKIY NWSGYPLLVQ KLGLDYSYDL APRAKIFRRD QGKVTDTASM KYIMRYNNYK KDPYSRGDPC NTICCREDLN SPNPSPGGCY DTKVADIYLA SQYTSYAISG PTVQGGLPVF RWDRFNKTLH QGMAEVYNFD FITMKPILKL DIK
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human FLJ22662.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
63,255 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (14656597..14720791, complement). Location: 12p13.1
3D Structure
ModBase 3D Structure for Q6P4A8
Immunogen
Full length human FLJ22662, aa1-223 (AAH00909.2).

Product Categories/Family for anti-PLBD1 antibody

Antibodies; Abs to Enzymes; Phospholipase
Applications Tested/Suitable for anti-PLBD1 antibody
Western Blot (WB)
Application Notes for anti-PLBD1 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-PLBD1 antibody

Western Blot analysis of FLJ22662 expression in transfected 293T cell line using MBS648915. Lane 1: FLJ22662 transfected lysate (24.64kD). Lane 2: Non-transfected lysate.
Rabbit Anti-PLBD1 Polyclonal Antibody – Cat# MBS648915

Immunofluorescence (IF) of anti-PLBD1 antibody

Immunofluorescence of HeLa cell using MBS648915 (20ug/ml).
Rabbit Anti-PLBD1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS648915

Other Notes

Small volumes of anti-PLBD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLBD1 purchase

MBS648915 is an antibody targeting PLBD1. Also known as PLBD1 (Phospholipase B-like 1, LAMA-like Protein 1, Lamina Ancestor Homolog 1, Phospholipase B Domain-containing Protein 1, FLJ22662). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLBD1. It may not necessarily be applicable to this product.

NCBI GI #
15029600
NCBI GeneID
79887
NCBI Accession #
AAH00909.2
UniProt Primary Accession #
Q6P4A8
UniProt Secondary Accession #
Q9BVV3; Q9H625; A8K4E9
UniProt Related Accession #
Q6P4A8
NCBI Official Full Name
PLBD1 protein
NCBI Official Synonym Full Names
phospholipase B domain containing 1
NCBI Official Symbol
PLBD1
UniProt Protein Name
Phospholipase B-like 1
UniProt Synonym Protein Names
LAMA-like protein 1; Lamina ancestor homolog 1; Phospholipase B domain-containing protein 1
Protein Family
Phospholipase
UniProt Gene Name
PLBD1
UniProt Entry Name
PLBL1_HUMAN
NCBI Protein Information
phospholipase B-like 1; PLB homolog 1; LAMA-like protein 1; lamina ancestor homolog 1; putative phospholipase B-like 1; phospholipase B domain-containing protein 1

UniProt Comments for PLBD1

Function: Phospholipase acting on various phospholipids including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids. May have a role in the defense against invading microorganisms and in the generation of lipid mediators of inflammation. Ref.4

Subunit structure: May exist as a non-covalently associated tetramer of two 22 kDa and two 42 kDa chains. Ref.4

Subcellular location: Cytoplasmic granule. Secreted Ref.4.

Tissue specificity: Expressed in neutrophils and monocytes. Ref.4

Post-translational modification: Proteolytic processing leading to a 22 kDa N-terminal and a 42 kDa C-terminal fragment appears necessary for activity, which seems to derive from the 42 kDa chain.

Sequence similarities: Belongs to the phospholipase B-like family.

Biophysicochemical propertiespH dependence:Optimum pH is 7.4. Ref.4

Sequence caution: The sequence AAH00909.2 differs from that shown. Reason: Erroneous initiation. The sequence BAB15442.1 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PLBD1 antibody

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