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FBXO30 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648948

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FBXO30, Polyclonal Antibody
Full Product Name
FBXO30 (F-box Only Protein 30, FBX30, FLJ41030, MGC21674)
Product Gene Name
anti-FBXO30 antibody
Product Synonym Names
Anti -FBXO30 (F-box Only Protein 30, FBX30, FLJ41030, MGC21674)
Immunogen Sequence
MEEELQHSHC VNCVSRRCMT RPEPGISCDL IGCPLVCGAV FHSCKADEHR LLCPFERVPC LNSDFGCPFT MARNKVAEHL EMCPASVVCC TMEWNRWPVS YADRKSYENL SRDVDEVAQL DMALALQDQR MLLESLKVAT MMSKATDKVS KPREQISVKS SVPEIPHANG LVSVDEESYG ALYQATVETT RSLAAALDIL NTATRDIGML NTSVPNDMDE QQNARESLED QNLKDQDHLY EEEIGAVGGI DYNDTNQNAQ SEQNGSSDLL CDLNTSSYDT SALCNGFPLE NICTQVIDQN QNLHGDSKQS NLTNGDCVAS SDGTSKPSSS LAVAAQLREI IPSSALPNGT VQHILMPDDE GEGELCWKKV DLGDVKNVDV LSFSHAPSFN FLSNSCWSKP KEDKAVDTSD LEVAEDPMGL QGIDLITAAL LFCLGDSPGG RGISDSRMAD IYHIDVGTQT FSLPSAILAT STMVGEIASA SACDHANPQL SNPSPFQTLG LDLVLECVAR YQPKQRSMFT FVCGQLFRRK EFSSHFKNVH GDIHAGLNGW MEQRCPLAYY GCTYSQRRFC PSIQGAKIIH DRHLRSFGVQ PCVSTVLVEP ARNCVLGLHN DHLSSLPFEV LQHIAGFLDG FSLCQLSCVS KLMRDVCGSL LQSRGMVILQ WGKRKYPEGN SSWQIKEKVW RFSTAFCSVN EWKFADILSM ADHLKKCSYN VVEKREEAIP LPCMCVTREL TKEGRSLRSV LKPVL
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human FBXO30.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
82,304 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (146119271..146135929, complement). Location: 6q24
OMIM
609101
3D Structure
ModBase 3D Structure for Q8TB52
Immunogen
Full length human FBXO30, aa1-745 (NP_115521.3).

Product Categories/Family for anti-FBXO30 antibody

Antibodies; Abs to Ubiquitin Ligases
Applications Tested/Suitable for anti-FBXO30 antibody
Western Blot (WB)
Application Notes for anti-FBXO30 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-FBXO30 antibody

FBXO30 polyclonal antibody. Western Blot analysis of FBXO30 expression in human colon.
Mouse Anti-FBXO30 Polyclonal Antibody – Cat# MBS648948

Western Blot (WB) of anti-FBXO30 antibody

Western Blot analysis of FBXO30 expression in transfected 293T cell line by FBXO30 polyclonal antibody. Lane 1: FBXO30 transfected lysate (81.95kD). Lane 2: Non-transfected lysate.
Mouse Anti-FBXO30 Polyclonal Antibody, Western Blot (WB) – Cat# MBS648948

Other Notes

Small volumes of anti-FBXO30 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FBXO30 purchase

MBS648948 is an antibody targeting FBXO30. Also known as FBXO30 (F-box Only Protein 30, FBX30, FLJ41030, MGC21674). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FBXO30. It may not necessarily be applicable to this product.

NCBI GI #
34577055
NCBI GeneID
84085
NCBI Accession #
NP_115521.3
UniProt Primary Accession #
Q8TB52
UniProt Secondary Accession #
Q9BXZ7
UniProt Related Accession #
Q8TB52
GenBank Nucleotide #
NM_032145.4
NCBI Official Full Name
F-box only protein 30
NCBI Official Synonym Full Names
F-box protein 30
NCBI Official Symbol
FBXO30
NCBI Official Synonym Symbols
Fbx30
UniProt Protein Name
F-box only protein 30
Protein Family
F-box only protein
UniProt Gene Name
FBXO30
UniProt Synonym Gene Names
FBX30
UniProt Entry Name
FBX30_HUMAN
NCBI Protein Information
F-box only protein 30; F-box domain protein; F-box only protein, helicase, 18

NCBI Summary for FBXO30

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. [provided by RefSeq, Jul 2008]
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UniProt Comments for FBXO30

Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex

By similarity.

Subunit structure: Directly interacts with SKP1 and CUL1

By similarity.

Sequence similarities: Contains 1 F-box domain.Contains 1 TRAF-type zinc finger.

Sequence caution: The sequence AAK30299.1 differs from that shown. Reason: Erroneous initiation. The sequence AAK30299.1 differs from that shown. Reason: Contaminating sequence. Sequence of unknown origin in the N-terminal part.
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Research Articles on FBXO30

1. Results suggest that D6S1581 is highly associated with nasopharyngeal carcinoma, and there may be one or more NPC associated genes near D6S1581, including FBXO30.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-FBXO30 antibody

 Disease Name  Pubmed Publications
 Atrophy Antibodies  >1 publications with FBXO30 and Atrophy
 Neoplasms Antibodies  >1 publications with FBXO30 and Neoplasms
 Hypertrophy Antibodies  >1 publications with FBXO30 and Hypertrophy

Organs/Tissues associated with anti-FBXO30 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with FBXO30 and Bone
 Muscle Antibodies  >1 publications with FBXO30 and Muscle
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