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SNAPC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648950

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SNAPC1, Polyclonal Antibody
Full Product Name
SNAPC1, ID (SNAPC1, SNAP43, snRNA-activating protein complex subunit 1, Proximal sequence element-binding transcription factor subunit gamma, Small nuclear RNA-activating complex polypeptide 1, snRNA-activating protein complex 43kD subunit)
Product Gene Name
anti-SNAPC1 antibody
Product Synonym Names
Anti -SNAPC1, ID (SNAPC1, SNAP43, snRNA-activating protein complex subunit 1, Proximal sequence element-binding transcription factor subunit gamma, Small nuclear RNA-activating complex polypeptide 1, snRNA-activating protein complex 43kD subunit)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
42,994 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (62229075..62263146). Location: 14q22
OMIM
600591
3D Structure
ModBase 3D Structure for Q16533
Immunogen
SNAPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-168 amino acids from the Central region of human SNAPC1.

Product Categories/Family for anti-SNAPC1 antibody

Antibodies; Abs to Transcription Factors
Applications Tested/Suitable for anti-SNAPC1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SNAPC1 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-SNAPC1 antibody

SNAPC1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SNAPC1 antibody detected the SNAPC1 protein (arrow).
Rabbit Anti-SNAPC1 Polyclonal Antibody – Cat# MBS648950

Western Blot (WB) of anti-SNAPC1 antibody

Western blot analysis of SNAPC1 (arrow) using rabbit polyclonal SNAPC1 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNAPC1 gene.
Rabbit Anti-SNAPC1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS648950

Other Notes

Small volumes of anti-SNAPC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNAPC1 purchase

MBS648950 is an antibody targeting SNAPC1. Also known as SNAPC1, ID (SNAPC1, SNAP43, snRNA-activating protein complex subunit 1, Proximal sequence element-binding transcription factor subunit gamma, Small nuclear RNA-activating complex polypeptide 1, snRNA-activating protein complex 43kD subunit). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SNAPC1. It may not necessarily be applicable to this product.

NCBI GI #
4507101
NCBI GeneID
6617
NCBI Accession #
NP_003073.1
UniProt Primary Accession #
Q16533
UniProt Related Accession #
Q16533
GenBank Nucleotide #
NM_003082.3
NCBI Official Full Name
snRNA-activating protein complex subunit 1
NCBI Official Synonym Full Names
small nuclear RNA activating complex, polypeptide 1, 43kDa
NCBI Official Symbol
SNAPC1
NCBI Official Synonym Symbols
SNAP43; PTFgamma
UniProt Protein Name
snRNA-activating protein complex subunit 1
UniProt Synonym Protein Names
Proximal sequence element-binding transcription factor subunit gamma; PSE-binding factor subunit gamma; PTF subunit gamma; Small nuclear RNA-activating complex polypeptide 1; snRNA-activating protein complex 43 kDa subunit
Protein Family
snRNA-activating protein complex
UniProt Gene Name
SNAPC1
UniProt Synonym Gene Names
SNAP43; SNAPc subunit 1; PSE-binding factor subunit gamma; PTF subunit gamma
UniProt Entry Name
SNPC1_HUMAN
NCBI Protein Information
snRNA-activating protein complex subunit 1; SNAPc subunit 1; PTF subunit gamma; SNAPc 43 kDa subunit; PSE-binding factor subunit gamma; snRNA-activating protein complex 43 kDa subunit; small nuclear RNA-activating complex polypeptide 1; proximal sequence element-binding transcription factor subunit gamma

UniProt Comments for SNAPC1

Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. Ref.5

Subunit structure: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC1 interacts with SNAPC3, SNAPC4 and TBP. Ref.4 Ref.5

Subcellular location: Nucleus.
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Research Articles on SNAPC1

1. SNAPC1 is a general transcriptional coactivator that functions through elongating RNAPII.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SNAPC1 antibody

 Reference Product  PubMed Publications
 TBP antibody  >6 publications with SNAPC1 and TBP
 SNAPC3 antibody  >5 publications with SNAPC1 and SNAPC3
 SNAPC4 antibody  >3 publications with SNAPC1 and SNAPC4
 SNAPC2 antibody  >3 publications with SNAPC1 and SNAPC2
 SNAPC5 antibody  >1 publications with SNAPC1 and SNAPC5

Pathways associated with anti-SNAPC1 antibody

 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies  RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
 RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies  RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
 RNA Polymerase III Transcription Pathway antibodies  RNA Polymerase III Transcription Pathway Diagram
 RNA Polymerase III Transcription Initiation Pathway antibodies  RNA Polymerase III Transcription Initiation Pathway Diagram
 RNA Polymerase III Transcription Initiation From Type 3 Promoter Pathway antibodies  RNA Polymerase III Transcription Initiation From Type 3 Promoter Pathway Diagram

Diseases associated with anti-SNAPC1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with SNAPC1 and Neoplasms
 Carcinoma, Squamous Cell Antibodies  >1 publications with SNAPC1 and Carcinoma, Squamous Cell
 Inflammation Antibodies  >1 publications with SNAPC1 and Inflammation
 Breast Neoplasms Antibodies  >1 publications with SNAPC1 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with SNAPC1 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >1 publications with SNAPC1 and Lung Neoplasms

Organs/Tissues associated with anti-SNAPC1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with SNAPC1 and Lung
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